C22.1 Intrahepatic bile duct carcinoma

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Cholangiocarcinoma

Excludes1 (never code together)

• malignant neoplasm of hepatic duct (C24.0)

Applies from C22 Malignant neoplasm of liver and intrahepatic bile ducts

Excludes1 (never code together)

• malignant neoplasm of biliary tract NOS (C24.9)
• secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)

Use additional code

• code to identify:
• alcohol abuse and dependence (F10.-)
• hepatitis B (B16.-, B18.0-B18.1)
• hepatitis C (B17.1-, B18.2)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 20 — Lung and Other Severe Cancers
• CMS-HCC V22: HCC 9 — Lung and Other Severe Cancers
• RxHCC V08: HCC 20 — Lung, Kidney, and Other Cancers; Secondary Cancer of Lymph Nodes and Other Sites
• ESRD V24: HCC 9

MS-DRG index

Defines the logic of DRG(s) 435-437 in MDC 07.

Approximate ICD-9-CM (GEMs)

• 155.1 Malignant neoplasm of intrahepatic bile ducts

Code annotations containing back-references to C22.1

Back-references to C22.1

• Type 1 Excludes: C24 Malignant neoplasm of other and unspecified parts of biliary tract ("malignant neoplasm of intrahepatic bile duct (C22.1)")

Diagnosis Index entries for C22.1

• Adenocarcinoma › bile duct type
• Adenocarcinoma › bile duct type › liver
• Adenocarcinoma › bile duct type › unspecified site
• Cancer › bile duct type liver
• Carcinoma (malignant) › bile duct › liver
• Carcinoma (malignant) › bile duct › unspecified site
• Cholangiocarcinoma › liver
• Cholangiocarcinoma › unspecified site
• Cystadenocarcinoma › bile duct

Nearby codes

• C22 Malignant neoplasm of liver and intrahepatic bile ducts
• C22.0 Liver cell carcinoma
• C22.1 Intrahepatic bile duct carcinoma (this code)
• C22.2 Hepatoblastoma
• C22.3 Angiosarcoma of liver
• C22.4 Other sarcomas of liver
• C22.7 Other specified carcinomas of liver
• C22.8 Malignant neoplasm of liver, primary, unspecified as to type