C46.1 Kaposi's sarcoma of soft tissue

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Kaposi's sarcoma of blood vessel
• Kaposi's sarcoma of connective tissue
• Kaposi's sarcoma of fascia
• Kaposi's sarcoma of ligament
• Kaposi's sarcoma of lymphatic(s) NEC
• Kaposi's sarcoma of muscle

Excludes2 (not included here)

• Kaposi's sarcoma of lymph glands and nodes (C46.3)

Applies from C46 Kaposi's sarcoma

Code first

• any human immunodeficiency virus [HIV] disease (B20)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 21 — Lymphoma and Other Cancers
• CMS-HCC V22: HCC 10 — Lymphoma and Other Cancers
• RxHCC V08: HCC 20 — Lung, Kidney, and Other Cancers; Secondary Cancer of Lymph Nodes and Other Sites
• ESRD V24: HCC 10

MS-DRG index

Defines the logic of DRG(s) 606-607 in MDC 09.

Approximate ICD-9-CM (GEMs)

• 176.1 Kaposi's sarcoma, soft tissue

Code annotations containing back-references to C46.1

Back-references to C46.1

• Type 1 Excludes: C47 Malignant neoplasm of peripheral nerves and autonomic nervous system ("Kaposi's sarcoma of soft tissue (C46.1)")
• Type 1 Excludes: C48 Malignant neoplasm of retroperitoneum and peritoneum ("Kaposi's sarcoma of connective tissue (C46.1)")
• Type 2 Excludes: C49 Malignant neoplasm of other connective and soft tissue ("Kaposi's sarcoma of soft tissue (C46.1)")

Back-references to C46

• Type 2 Excludes: D47.Z2 Castleman disease ("Kaposi's sarcoma (C46.-)")

Diagnosis Index entries for C46.1

• Kaposi's › sarcoma › connective tissue
• Sarcoma (of) › Kaposi's › connective tissue

Nearby codes

• C46 Kaposi's sarcoma
• C46.0 Kaposi's sarcoma of skin
• C46.1 Kaposi's sarcoma of soft tissue (this code)
• C46.2 Kaposi's sarcoma of palate
• C46.3 Kaposi's sarcoma of lymph nodes
• C46.4 Kaposi's sarcoma of gastrointestinal sites
• C46.5 Kaposi's sarcoma of lung
• C46.50 Kaposi's sarcoma of unspecified lung