C82.21 Follicular lymphoma grade III, unspecified, lymph nodes of head, face, and neck

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from C82 Follicular lymphoma

Includes

• follicular lymphoma with or without diffuse areas

Excludes1 (never code together)

• mature T/NK-cell lymphomas (C84.-)
• personal history of non-Hodgkin lymphoma (Z85.72)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 21 — Lymphoma and Other Cancers
• CMS-HCC V22: HCC 10 — Lymphoma and Other Cancers
• RxHCC V08: HCC 21 — Lymphomas and Other Hematologic Cancers
• ESRD V24: HCC 10

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 202.01 Nodular lymphoma, lymph nodes of head, face, and neck (approximate)

Code annotations containing back-references to C82.21

Back-references to C82

• Type 1 Excludes: C26.1 Malignant neoplasm of spleen ("non-Hodgkin lymphoma (C82-C85)")
• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: C77 Secondary and unspecified malignant neoplasm of lymph nodes ("malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)")
• Code Also: D47.02 Systemic mastocytosis ("non-Hodgkin lymphoma (C82-C85)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C82.18 Follicular lymphoma grade II, lymph nodes of multiple sites
• C82.19 Follicular lymphoma grade II, extranodal and solid organ sites
• C82.1A Follicular lymphoma grade II, in remission
• C82.2 Follicular lymphoma grade III, unspecified
• C82.20 Follicular lymphoma grade III, unspecified, unspecified site
• C82.21 Follicular lymphoma grade III, unspecified, lymph nodes of head, face, and neck (this code)
• C82.22 Follicular lymphoma grade III, unspecified, intrathoracic lymph nodes
• C82.23 Follicular lymphoma grade III, unspecified, intra-abdominal lymph nodes
• C82.24 Follicular lymphoma grade III, unspecified, lymph nodes of axilla and upper limb
• C82.25 Follicular lymphoma grade III, unspecified, lymph nodes of inguinal region and lower limb
• C82.26 Follicular lymphoma grade III, unspecified, intrapelvic lymph nodes