D47.02 Systemic mastocytosis

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Indolent systemic mastocytosis
• Isolated bone marrow mastocytosis
• Smoldering systemic mastocytosis
• Systemic mastocytosis, with an associated hematological non-mast cell lineage disease (SM-AHNMD)

Excludes1 (never code together)

• aggressive systemic mastocytosis (C96.21)
• mast cell leukemia (C94.3-)

Code also

• , if applicable, any associated hematological non-mast cell lineage disease, such as:
• acute myeloid leukemia (C92.6-, C92.A-)
• chronic myelomonocytic leukemia (C93.1-)
• essential thrombocytosis (D47.3)
• hypereosinophilic syndrome (D72.1)
• myelodysplastic syndrome (D46.9)
• myeloproliferative syndrome (D47.1)
• non-Hodgkin lymphoma (C82-C85)
• plasma cell myeloma (C90.0-)
• polycythemia vera (D45)

Applies from D47.0 Mast cell neoplasms of uncertain behavior

Excludes1 (never code together)

• congenital cutaneous mastocytosis (Q82.2)
• histiocytic neoplasms of uncertain behavior (D47.Z9)
• malignant mast cell neoplasm (C96.2-)

Risk adjustment (HCC)

• RxHCC V08: HCC 21 — Lymphomas and Other Hematologic Cancers

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 238.5 Neoplasm of uncertain behavior of histiocytic and mast cells (approximate)

Code annotations containing back-references to D47.02

Back-references to D47.02

• Type 1 Excludes: C96.2 Malignant mast cell neoplasm ("indolent mastocytosis (D47.02)")
• Type 1 Excludes: D89.4 Mast cell activation syndrome and related disorders ("(indolent) systemic mastocytosis (D47.02)")
• Type 1 Excludes: D89.4 Mast cell activation syndrome and related disorders ("systemic mastocytosis associated with a clonal hematologic non-mast cell lineage disease (SM-AHNMD) (D47.02)")
• Type 1 Excludes: Q82.2 Congenital cutaneous mastocytosis ("systemic mastocytosis (D47.02)")

Diagnosis Index entries for D47.02

• Disease, diseased › systemic tissue mast cell
• Mast cell › disease, systemic tissue
• Mastocytosis › indolent systemic
• Mastocytosis › isolated bone marrow
• Mastocytosis › systemic (indolent) (smoldering) › with an associated hematological non-mast cell lineage disease (SM-AHNMD)

Nearby codes

• D47 Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
• D47.0 Mast cell neoplasms of uncertain behavior
• D47.01 Cutaneous mastocytosis
• D47.02 Systemic mastocytosis (this code)
• D47.09 Other mast cell neoplasms of uncertain behavior
• D47.1 Chronic myeloproliferative disease
• D47.2 Monoclonal gammopathy
• D47.3 Essential (hemorrhagic) thrombocythemia
• D47.4 Osteomyelofibrosis