C83.31 Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from C83 Non-follicular lymphoma

Excludes1 (never code together)

• personal history of non-Hodgkin lymphoma (Z85.72)

Applies from C83.3 Diffuse large B-cell lymphoma

Applicable to

• Anaplastic diffuse large B-cell lymphoma
• CD30-positive diffuse large B-cell lymphoma
• Centroblastic diffuse large B-cell lymphoma
• Diffuse large B-cell lymphoma, subtype not specified
• Immunoblastic diffuse large B-cell lymphoma
• Plasmablastic diffuse large B-cell lymphoma
• T-cell rich diffuse large B-cell lymphoma

Excludes1 (never code together)

• mediastinal (thymic) large B-cell lymphoma (C85.2-)
• mature T/NK-cell lymphomas (C84.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 20 — Lung and Other Severe Cancers
• CMS-HCC V22: HCC 10 — Lymphoma and Other Cancers
• RxHCC V08: HCC 21 — Lymphomas and Other Hematologic Cancers
• ESRD V24: HCC 10

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 200.01 Reticulosarcoma, lymph nodes of head, face, and neck (approximate)
• 200.71 Large cell lymphoma, lymph nodes of head, face, and neck (approximate)

Code annotations containing back-references to C83.31

Back-references to C83.3

• Type 1 Excludes: C83.8 Other non-follicular lymphoma ("T-cell rich B-cell lymphoma (C83.3-)")
• Type 1 Excludes: C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] ("high malignant (diffuse large B-cell) lymphoma (C83.3-)")

Back-references to C83

• Type 1 Excludes: C26.1 Malignant neoplasm of spleen ("non-Hodgkin lymphoma (C82-C85)")
• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: C77 Secondary and unspecified malignant neoplasm of lymph nodes ("malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)")
• Code Also: D47.02 Systemic mastocytosis ("non-Hodgkin lymphoma (C82-C85)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C83.18 Mantle cell lymphoma, lymph nodes of multiple sites
• C83.19 Mantle cell lymphoma, extranodal and solid organ sites
• C83.1A Mantle cell lymphoma, in remission
• C83.3 Diffuse large B-cell lymphoma
• C83.30 Diffuse large B-cell lymphoma, unspecified site
• C83.31 Diffuse large B-cell lymphoma, lymph nodes of head, face, and neck (this code)
• C83.32 Diffuse large B-cell lymphoma, intrathoracic lymph nodes
• C83.33 Diffuse large B-cell lymphoma, intra-abdominal lymph nodes
• C83.34 Diffuse large B-cell lymphoma, lymph nodes of axilla and upper limb
• C83.35 Diffuse large B-cell lymphoma, lymph nodes of inguinal region and lower limb
• C83.36 Diffuse large B-cell lymphoma, intrapelvic lymph nodes