C91.Z2 Other lymphoid leukemia, in relapse

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from C91 Lymphoid leukemia

Excludes1 (never code together)

• personal history of leukemia (Z85.6)

Applies from C91.Z Other lymphoid leukemia

Applicable to

• T-cell large granular lymphocytic leukemia (associated with rheumatoid arthritis)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 22 — Bladder, Colorectal, and Other Cancers
• CMS-HCC V22: HCC 10 — Lymphoma and Other Cancers
• RxHCC V08: HCC 19 — Leukemias and Other Hematologic Cancers
• ESRD V24: HCC 10

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 204.82 Other lymphoid leukemia, in relapse (approximate)

Code annotations containing back-references to C91.Z2

Back-references to C91

• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: D72.8 Other specified disorders of white blood cells ("leukemia (C91-C95)")
• Type 1 Excludes: D72.825 Bandemia ("leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)")
• Code First: M36.1 Arthropathy in neoplastic disease ("leukemia (C91-C95)")
• Code First: N16 Renal tubulo-interstitial disorders in diseases classified elsewhere ("leukemia (C91-C95)")
• Code First: R50.81 Fever presenting with conditions classified elsewhere ("leukemia (C91-C95)")
• Type 1 Excludes: T66 Radiation sickness, unspecified ("leukemia (C91-C95)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C91.A1 Mature B-cell leukemia Burkitt-type, in remission
• C91.A2 Mature B-cell leukemia Burkitt-type, in relapse
• C91.Z Other lymphoid leukemia
• C91.Z0 Other lymphoid leukemia not having achieved remission
• C91.Z1 Other lymphoid leukemia, in remission
• C91.Z2 Other lymphoid leukemia, in relapse (this code)
• C91.9 Lymphoid leukemia, unspecified
• C91.90 Lymphoid leukemia, unspecified not having achieved remission
• C91.91 Lymphoid leukemia, unspecified, in remission
• C91.92 Lymphoid leukemia, unspecified, in relapse