C92.41 Acute promyelocytic leukemia, in remission

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from C92 Myeloid leukemia

Includes

• granulocytic leukemia
• myelogenous leukemia

Excludes1 (never code together)

• personal history of leukemia (Z85.6)

Code also

• , if applicable, pancytopenia (acquired) (D61.818)

Applies from C92.4 Acute promyelocytic leukemia

Applicable to

• AML M3
• AML Me with t(15;17) and variants

Risk adjustment (HCC)

• CMS-HCC V28: HCC 22 — Bladder, Colorectal, and Other Cancers
• CMS-HCC V22: HCC 8 — Metastatic Cancer and Acute Leukemia
• RxHCC V08: HCC 21 — Lymphomas and Other Hematologic Cancers
• ESRD V24: HCC 8

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 205.01 Acute myeloid leukemia, in remission (approximate)

Code annotations containing back-references to C92.41

Back-references to C92

• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: D72.8 Other specified disorders of white blood cells ("leukemia (C91-C95)")
• Type 1 Excludes: D72.825 Bandemia ("leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)")
• Code First: M36.1 Arthropathy in neoplastic disease ("leukemia (C91-C95)")
• Code First: N16 Renal tubulo-interstitial disorders in diseases classified elsewhere ("leukemia (C91-C95)")
• Code First: R50.81 Fever presenting with conditions classified elsewhere ("leukemia (C91-C95)")
• Type 1 Excludes: T66 Radiation sickness, unspecified ("leukemia (C91-C95)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C92.30 Myeloid sarcoma, not having achieved remission
• C92.31 Myeloid sarcoma, in remission
• C92.32 Myeloid sarcoma, in relapse
• C92.4 Acute promyelocytic leukemia
• C92.40 Acute promyelocytic leukemia, not having achieved remission
• C92.41 Acute promyelocytic leukemia, in remission (this code)
• C92.42 Acute promyelocytic leukemia, in relapse
• C92.5 Acute myelomonocytic leukemia
• C92.50 Acute myelomonocytic leukemia, not having achieved remission
• C92.51 Acute myelomonocytic leukemia, in remission
• C92.52 Acute myelomonocytic leukemia, in relapse