C95.00 Acute leukemia of unspecified cell type not having achieved remission

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Acute leukemia of unspecified cell type with failed remission
• Acute leukemia NOS

Applies from C95 Leukemia of unspecified cell type

Excludes1 (never code together)

• personal history of leukemia (Z85.6)

Applies from C95.0 Acute leukemia of unspecified cell type

Applicable to

• Acute bilineal leukemia
• Acute mixed lineage leukemia
• Biphenotypic acute leukemia
• Stem cell leukemia of unclear lineage

Excludes1 (never code together)

• acute exacerbation of unspecified chronic leukemia (C95.10)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 18 — Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid
• CMS-HCC V22: HCC 8 — Metastatic Cancer and Acute Leukemia
• RxHCC V08: HCC 19 — Leukemias and Other Hematologic Cancers
• ESRD V24: HCC 8

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 208.00 Acute leukemia of unspecified cell type, without mention of having achieved remission

Code annotations containing back-references to C95.00

Back-references to C95

• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: D72.8 Other specified disorders of white blood cells ("leukemia (C91-C95)")
• Type 1 Excludes: D72.825 Bandemia ("leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)")
• Code First: M36.1 Arthropathy in neoplastic disease ("leukemia (C91-C95)")
• Code First: N16 Renal tubulo-interstitial disorders in diseases classified elsewhere ("leukemia (C91-C95)")
• Code First: R50.81 Fever presenting with conditions classified elsewhere ("leukemia (C91-C95)")
• Type 1 Excludes: T66 Radiation sickness, unspecified ("leukemia (C91-C95)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C95 Leukemia of unspecified cell type
• C95.0 Acute leukemia of unspecified cell type
• C95.00 Acute leukemia of unspecified cell type not having achieved remission (this code)
• C95.01 Acute leukemia of unspecified cell type, in remission
• C95.02 Acute leukemia of unspecified cell type, in relapse
• C95.1 Chronic leukemia of unspecified cell type
• C95.10 Chronic leukemia of unspecified cell type not having achieved remission
• C95.11 Chronic leukemia of unspecified cell type, in remission