D53.1 Other megaloblastic anemias, not elsewhere classified

Billable ICD-10-CM code, FY2026.

Applicable to

• Megaloblastic anemia NOS

Excludes1 (never code together)

• Di Guglielmo's disease (C94.0)

Applies from D53 Other nutritional anemias

Includes

• megaloblastic anemia unresponsive to vitamin B12 or folate therapy

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 281.3 Other specified megaloblastic anemias not elsewhere classified

Code annotations containing back-references to D53.1

Back-references to D53

• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D53.1

• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › achrestic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › deficiency › combined B12 and folate
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › dimorphic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › diphasic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › megaloblastic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › megaloblastic › combined B12 and folate deficiency
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › megaloblastic › refractory
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › megaloblastic › specified type NEC
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › megalocytic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › refractory › megaloblastic
• Megalocytic anemia

Nearby codes

• D53 Other nutritional anemias
• D53.0 Protein deficiency anemia
• D53.1 Other megaloblastic anemias, not elsewhere classified (this code)
• D53.2 Scorbutic anemia
• D53.8 Other specified nutritional anemias
• D53.9 Nutritional anemia, unspecified