D57.812 Other sickle-cell disorders with splenic sequestration

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applies from D57 Sickle-cell disorders

Excludes1 (never code together)

• other hemoglobinopathies (D58.-)

Use additional code

• code for any associated fever (R50.81)

Applies from D57.8 Other sickle-cell disorders

Applicable to

• Hb-SD disease
• Hb-SE disease

Risk adjustment (HCC)

• CMS-HCC V28: HCC 108 — Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major
• CMS-HCC V22: HCC 46 — Severe Hematological Disorders
• ESRD V24: HCC 46

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 282.69 Other sickle-cell disease with crisis (approximate)
• 289.52 Splenic sequestration (approximate)

Code annotations containing back-references to D57.812

Back-references to D57.8

• Code First: N08 Glomerular disorders in diseases classified elsewhere ("sickle-cell disease (D57.0-D57.8)")

Back-references to D57

• Type 1 Excludes: D56.8 Other thalassemias ("sickle-cell anemia (D57.-)")
• Code First: H36 Retinal disorders in diseases classified elsewhere ("sickle-cell disorders (D57.-)")
• Code First: M14.8 Arthropathies in other specified diseases classified elsewhere ("sickle-cell disorders (D57.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Code First: R50.81 Fever presenting with conditions classified elsewhere ("sickle-cell disease (D57.-)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")
• Code Also: Z71.87 Encounter for pediatric-to-adult transition counseling ("sickle-cell disorder (D57.-)")

Diagnosis Index entries for D57.812

• Disease, diseased › sickle-cell › Hb-SD › with › splenic sequestration
• Disease, diseased › sickle-cell › Hb-SE › with › splenic sequestration
• Disease, diseased › sickle-cell › specified NEC › with › splenic sequestration
• Disease, diseased › sickle-cell › spherocytosis › with › splenic sequestration

Nearby codes

• D57.459 Sickle-cell thalassemia beta plus with crisis, unspecified
• D57.8 Other sickle-cell disorders
• D57.80 Other sickle-cell disorders without crisis
• D57.81 Other sickle-cell disorders with crisis
• D57.811 Other sickle-cell disorders with acute chest syndrome
• D57.812 Other sickle-cell disorders with splenic sequestration (this code)
• D57.813 Other sickle-cell disorders with cerebral vascular involvement
• D57.814 Other sickle-cell disorders with dactylitis
• D57.818 Other sickle-cell disorders with crisis with other specified complication
• D57.819 Other sickle-cell disorders with crisis, unspecified