D56.8 Other thalassemias

Billable ICD-10-CM code, FY2026.

Applicable to

• Dominant thalassemia
• Hemoglobin C thalassemia
• Mixed thalassemia
• Thalassemia with other hemoglobinopathy

Excludes1 (never code together)

• hemoglobin C disease (D58.2)
• hemoglobin E disease (D58.2)
• other hemoglobinopathies (D58.2)
• sickle-cell anemia (D57.-)
• sickle-cell thalassemia (D57.4-)

Applies from D56 Thalassemia

Excludes1 (never code together)

• sickle-cell thalassemia (D57.4-)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 791 in MDC 15.

Approximate ICD-9-CM (GEMs)

• 282.49 Other thalassemia

Code annotations containing back-references to D56.8

Back-references to D56.8

• Type 1 Excludes: D58.2 Other hemoglobinopathies ("other hemoglobinopathies with thalassemia (D56.8)")

Back-references to D56

• Code First: M36.3 Arthropathy in other blood disorders ("thalassemia (D56.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D56.8

• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › microcytic (hypochromic) › familial
• Disease, diseased › hemoglobin or Hb › C (Hb-C) › thalassemia
• Hemoglobinopathy (mixed) › with thalassemia
• Thalassemia (anemia) (disease) › with other hemoglobinopathy
• Thalassemia (anemia) (disease) › dominant
• Thalassemia (anemia) (disease) › hemoglobin › C
• Thalassemia (anemia) (disease) › mixed
• Thalassemia (anemia) (disease) › specified type NEC
• Thalassemia (anemia) (disease) › variants
• Variants, thalassemic

Nearby codes

• D56.1 Beta thalassemia
• D56.2 Delta-beta thalassemia
• D56.3 Thalassemia minor
• D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
• D56.5 Hemoglobin E-beta thalassemia
• D56.8 Other thalassemias (this code)
• D56.9 Thalassemia, unspecified