D56.3 Thalassemia minor

Billable ICD-10-CM code, FY2026.

Applicable to

• Alpha thalassemia minor
• Alpha thalassemia silent carrier
• Alpha thalassemia trait
• Beta thalassemia minor
• Beta thalassemia trait
• Delta-beta thalassemia minor
• Delta-beta thalassemia trait
• Thalassemia trait NOS

Excludes1 (never code together)

• alpha thalassemia (D56.0)
• beta thalassemia (D56.1)
• delta-beta thalassemia (D56.2)
• hemoglobin E-beta thalassemia (D56.5)
• sickle-cell trait (D57.3)

Applies from D56 Thalassemia

Excludes1 (never code together)

• sickle-cell thalassemia (D57.4-)

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 282.46 Thalassemia minor

Code annotations containing back-references to D56.3

Back-references to D56.3

• Type 1 Excludes: D56.0 Alpha thalassemia ("alpha thalassemia trait or minor (D56.3)")
• Type 1 Excludes: D56.0 Alpha thalassemia ("asymptomatic alpha thalassemia (D56.3)")
• Type 1 Excludes: D56.1 Beta thalassemia ("beta thalassemia minor (D56.3)")
• Type 1 Excludes: D56.1 Beta thalassemia ("beta thalassemia trait (D56.3)")
• Type 1 Excludes: D56.2 Delta-beta thalassemia ("delta-beta thalassemia minor (D56.3)")
• Type 1 Excludes: D56.2 Delta-beta thalassemia ("delta-beta thalassemia trait (D56.3)")
• Type 1 Excludes: D56.5 Hemoglobin E-beta thalassemia ("beta thalassemia minor (D56.3)")
• Type 1 Excludes: D56.5 Hemoglobin E-beta thalassemia ("beta thalassemia trait (D56.3)")
• Type 1 Excludes: D56.5 Hemoglobin E-beta thalassemia ("delta-beta thalassemia trait (D56.3)")

Back-references to D56

• Code First: M36.3 Arthropathy in other blood disorders ("thalassemia (D56.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D56.3

• Thalassemia (anemia) (disease) › alpha (major) (severe) (triple gene defect) › minor
• Thalassemia (anemia) (disease) › alpha (major) (severe) (triple gene defect) › silent carrier
• Thalassemia (anemia) (disease) › alpha (major) (severe) (triple gene defect) › trait
• Thalassemia (anemia) (disease) › beta (severe) › minor
• Thalassemia (anemia) (disease) › beta (severe) › trait
• Thalassemia (anemia) (disease) › delta-beta (homozygous) › minor
• Thalassemia (anemia) (disease) › delta-beta (homozygous) › trait
• Thalassemia (anemia) (disease) › minor
• Thalassemia (anemia) (disease) › trait
• Trait (s) › hemoglobin › abnormal NEC › with thalassemia
• Trait (s) › Lepore

Nearby codes

• D56 Thalassemia
• D56.0 Alpha thalassemia
• D56.1 Beta thalassemia
• D56.2 Delta-beta thalassemia
• D56.3 Thalassemia minor (this code)
• D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
• D56.5 Hemoglobin E-beta thalassemia
• D56.8 Other thalassemias
• D56.9 Thalassemia, unspecified