D56.2 Delta-beta thalassemia

Billable ICD-10-CM code, FY2026.

Applicable to

• Homozygous delta-beta thalassemia

Excludes1 (never code together)

• delta-beta thalassemia minor (D56.3)
• delta-beta thalassemia trait (D56.3)

Applies from D56 Thalassemia

Excludes1 (never code together)

• sickle-cell thalassemia (D57.4-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 108 — Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major
• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 791 in MDC 15.

Approximate ICD-9-CM (GEMs)

• 282.45 Delta-beta thalassemia

Code annotations containing back-references to D56.2

Back-references to D56.2

• Type 1 Excludes: D56.1 Beta thalassemia ("delta-beta thalassemia (D56.2)")
• Type 1 Excludes: D56.3 Thalassemia minor ("delta-beta thalassemia (D56.2)")
• Type 1 Excludes: D56.5 Hemoglobin E-beta thalassemia ("delta-beta thalassemia (D56.2)")

Back-references to D56

• Code First: M36.3 Arthropathy in other blood disorders ("thalassemia (D56.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D56.2

• Thalassemia (anemia) (disease) › delta-beta (homozygous)

Nearby codes

• D56 Thalassemia
• D56.0 Alpha thalassemia
• D56.1 Beta thalassemia
• D56.2 Delta-beta thalassemia (this code)
• D56.3 Thalassemia minor
• D56.4 Hereditary persistence of fetal hemoglobin [HPFH]
• D56.5 Hemoglobin E-beta thalassemia
• D56.8 Other thalassemias
• D56.9 Thalassemia, unspecified