D58.2 Other hemoglobinopathies

Billable ICD-10-CM code, FY2026.

Applicable to

• Abnormal hemoglobin NOS
• Congenital Heinz body anemia
• Hb-C disease
• Hb-D disease
• Hb-E disease
• Hemoglobinopathy NOS
• Unstable hemoglobin hemolytic disease

Excludes1 (never code together)

• familial polycythemia (D75.0)
• Hb-M disease (D74.0)
• hemoglobin E-beta thalassemia (D56.5)
• hereditary persistence of fetal hemoglobin [HPFH] (D56.4)
• high-altitude polycythemia (D75.1)
• methemoglobinemia (D74.-)
• other hemoglobinopathies with thalassemia (D56.8)

Applies from D58 Other hereditary hemolytic anemias

Excludes1 (never code together)

• hemolytic anemia of the newborn (P55.-)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 282.7 Other hemoglobinopathies (approximate)

Code annotations containing back-references to D58.2

Back-references to D58.2

• Type 1 Excludes: D56.5 Hemoglobin E-beta thalassemia ("hemoglobin E disease (D58.2)")
• Type 1 Excludes: D56.5 Hemoglobin E-beta thalassemia ("other hemoglobinopathies (D58.2)")
• Type 1 Excludes: D56.8 Other thalassemias ("hemoglobin C disease (D58.2)")
• Type 1 Excludes: D56.8 Other thalassemias ("hemoglobin E disease (D58.2)")
• Type 1 Excludes: D56.8 Other thalassemias ("other hemoglobinopathies (D58.2)")
• Code First: M36.3 Arthropathy in other blood disorders ("other hemoglobinopathies (D58.2)")

Back-references to D58

• Type 1 Excludes: D57 Sickle-cell disorders ("other hemoglobinopathies (D58.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D58.2

• Abnormal, abnormality, abnormalities › hemoglobin (disease)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › congenital › Heinz body
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › Heinz body, congenital
• Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) › in (due to) › hemoglobinopathy NEC
• Arthropathy › in (due to) › hemoglobinopathy NEC
• Disease, diseased › hemoglobin or Hb › abnormal (mixed) NEC
• Disease, diseased › hemoglobin or Hb › C (Hb-C)
• Disease, diseased › hemoglobin or Hb › C (Hb-C) › with other abnormal hemoglobin NEC
• Disease, diseased › hemoglobin or Hb › Constant Spring
• Disease, diseased › hemoglobin or Hb › D (Hb-D)
• Disease, diseased › hemoglobin or Hb › E (Hb-E)
• Disease, diseased › hemoglobin or Hb › unstable, hemolytic
• Disease, diseased › hemolytic (newborn) › unstable hemoglobin
• Heinz body anemia, congenital
• Hemoglobin › Constant Spring
• Hemoglobinopathy (mixed)
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › carpus
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › clavicle
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › femur
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › fibula
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › finger
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › humerus
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › ilium
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › ischium
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › metacarpus
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › metatarsus
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › multiple sites
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › neck
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › radius
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › rib
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › scapula
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › skull
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › specified NEC
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › tarsus
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › tibia
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › toe
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › ulna
• Osteonecrosis › secondary NEC › due to › hemoglobinopathy NEC › vertebra
• Trait (s) › hemoglobin › abnormal NEC

Nearby codes

• D58 Other hereditary hemolytic anemias
• D58.0 Hereditary spherocytosis
• D58.1 Hereditary elliptocytosis
• D58.2 Other hemoglobinopathies (this code)
• D58.8 Other specified hereditary hemolytic anemias
• D58.9 Hereditary hemolytic anemia, unspecified