D61.82 Myelophthisis

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Leukoerythroblastic anemia
• Myelophthisic anemia
• Panmyelophthisis

Excludes1 (never code together)

• idiopathic myelofibrosis (D47.1)
• myelofibrosis NOS (D75.81)
• myelofibrosis with myeloid metaplasia (D47.4)
• primary myelofibrosis (D47.1)
• secondary myelofibrosis (D75.81)

Code also

• the underlying disorder, such as:
• malignant neoplasm of breast (C50.-)
• tuberculosis (A15.-)

Applies from D61 Other aplastic anemias and other bone marrow failure syndromes

Excludes2 (not included here)

• neutropenia (D70.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 109 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
• CMS-HCC V22: HCC 46 — Severe Hematological Disorders
• RxHCC V08: HCC 96 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
• ESRD V24: HCC 46

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 284.2 Myelophthisis

Code annotations containing back-references to D61.82

Back-references to D61.82

• Type 1 Excludes: D47.1 Chronic myeloproliferative disease ("myelophthisic anemia (D61.82)")
• Type 1 Excludes: D47.1 Chronic myeloproliferative disease ("myelophthisis (D61.82)")
• Type 1 Excludes: D61.81 Pancytopenia ("pancytopenia (due to) (with) bone marrow infiltration (D61.82)")
• Type 1 Excludes: D61.81 Pancytopenia ("pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)")
• Type 1 Excludes: D75.81 Myelofibrosis ("leukoerythroblastic anemia (D61.82)")
• Type 1 Excludes: D75.81 Myelofibrosis ("myelophthisic anemia (D61.82)")
• Type 1 Excludes: D75.81 Myelofibrosis ("myelophthisis (D61.82)")

Back-references to D61

• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D61.82

• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › leukoerythroblastic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › myelophthisic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › normocytic (infectional) › myelophthisic
• Myelophthisis
• Panmyelophthisis

Nearby codes

• D61.8 Other specified aplastic anemias and other bone marrow failure syndromes
• D61.81 Pancytopenia
• D61.810 Antineoplastic chemotherapy induced pancytopenia
• D61.811 Other drug-induced pancytopenia
• D61.818 Other pancytopenia
• D61.82 Myelophthisis (this code)
• D61.89 Other specified aplastic anemias and other bone marrow failure syndromes
• D61.9 Aplastic anemia, unspecified