D69.42 Congenital and hereditary thrombocytopenia purpura

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Congenital thrombocytopenia
• Hereditary thrombocytopenia

Code first

• congential or hereditary disorder, such as:
• thrombocytopenia with absent radius (TAR syndrome) (Q87.2)

Applies from D69 Purpura and other hemorrhagic conditions

Excludes1 (never code together)

• benign hypergammaglobulinemic purpura (D89.0)
• cryoglobulinemic purpura (D89.1)
• essential (hemorrhagic) thrombocythemia (D47.3)
• hemorrhagic thrombocythemia (D47.3)
• purpura fulminans (D65)
• thrombotic thrombocytopenic purpura (M31.19)
• Waldenström hypergammaglobulinemic purpura (D89.0)

Applies from D69.4 Other primary thrombocytopenia

Excludes1 (never code together)

• transient neonatal thrombocytopenia (P61.0)
• Wiskott-Aldrich syndrome (D82.0)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 112 — Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions
• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 813 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 287.33 Congenital and hereditary thrombocytopenic purpura

Code annotations containing back-references to D69.42

Back-references to D69

• Type 1 Excludes: R23.3 Spontaneous ecchymoses ("purpura (D69.-)")

Diagnosis Index entries for D69.42

• Purpura › thrombocytopenic › congenital
• Purpura › thrombocytopenic › hereditary
• Thrombocytopenia, thrombocytopenic › congenital
• Thrombocytopenia, thrombocytopenic › hereditary

Nearby codes

• D69.1 Qualitative platelet defects
• D69.2 Other nonthrombocytopenic purpura
• D69.3 Immune thrombocytopenic purpura
• D69.4 Other primary thrombocytopenia
• D69.41 Evans syndrome
• D69.42 Congenital and hereditary thrombocytopenia purpura (this code)
• D69.49 Other primary thrombocytopenia
• D69.5 Secondary thrombocytopenia
• D69.51 Posttransfusion purpura
• D69.59 Other secondary thrombocytopenia
• D69.6 Thrombocytopenia, unspecified