D82.1 Di George's syndrome

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Pharyngeal pouch syndrome
• Thymic alymphoplasia
• Thymic aplasia or hypoplasia with immunodeficiency

Applies from D82 Immunodeficiency associated with other major defects

Excludes1 (never code together)

• ataxia telangiectasia [Louis-Bar] (G11.3)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 115 — Specified Immunodeficiencies and White Blood Cell Disorders
• CMS-HCC V22: HCC 47 — Disorders of Immunity
• RxHCC V08: HCC 99 — Immune Disorders
• ESRD V24: HCC 47

MS-DRG index

Defines the logic of DRG(s) 808-810 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 279.11 Digeorge's syndrome

Code annotations containing back-references to D82.1

Back-references to D82.1

• Type 1 Excludes: E20 Hypoparathyroidism ("Di George's syndrome (D82.1)")
• Type 1 Excludes: E32 Diseases of thymus ("aplasia or hypoplasia of thymus with immunodeficiency (D82.1)")
• Type 1 Excludes: E32.8 Other diseases of thymus ("aplasia or hypoplasia with immunodeficiency (D82.1)")
• Type 1 Excludes: Q38.7 Congenital pharyngeal pouch ("pharyngeal pouch syndrome (D82.1)")

Back-references to D82

• Type 1 Excludes: D72 Other disorders of white blood cells ("immunity disorders (D80-D89)")
• Type 1 Excludes: D84.81 Immunodeficiency due to conditions classified elsewhere ("certain disorders involving the immune mechanism (D80-D83, D84.0, D84.1, D84.9)")

Diagnosis Index entries for D82.1

• Alymphocytosis › thymic (with immunodeficiency)
• Alymphoplasia, thymic
• Aplasia › parathyroid-thymic
• Aplasia › thymic, with immunodeficiency
• Di George's syndrome
• DiGeorge's syndrome (thymic hypoplasia)
• Dysplasia › thymic, with immunodeficiency
• Hypoplasia, hypoplastic › thymic, with immunodeficiency
• Hypoplasia, hypoplastic › thymus (gland) › with immunodeficiency
• Pharyngeal pouch syndrome
• Syndrome › di George's
• Syndrome › pharyngeal pouch

Nearby codes

• D82 Immunodeficiency associated with other major defects
• D82.0 Wiskott-Aldrich syndrome
• D82.1 Di George's syndrome (this code)
• D82.2 Immunodeficiency with short-limbed stature
• D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
• D82.4 Hyperimmunoglobulin E [IgE] syndrome
• D82.8 Immunodeficiency associated with other specified major defects
• D82.9 Immunodeficiency associated with major defect, unspecified