D82.9 Immunodeficiency associated with major defect, unspecified

Billable ICD-10-CM code, FY2026.

Applies from D82 Immunodeficiency associated with other major defects

Excludes1 (never code together)

• ataxia telangiectasia [Louis-Bar] (G11.3)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 47 — Disorders of Immunity
• RxHCC V08: HCC 99 — Immune Disorders
• ESRD V24: HCC 47

MS-DRG index

Defines the logic of DRG(s) 814-816 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 279.8 Other specified disorders involving the immune mechanism (approximate)

Code annotations containing back-references to D82.9

Back-references to D82

• Type 1 Excludes: D72 Other disorders of white blood cells ("immunity disorders (D80-D89)")
• Type 1 Excludes: D84.81 Immunodeficiency due to conditions classified elsewhere ("certain disorders involving the immune mechanism (D80-D83, D84.0, D84.1, D84.9)")

Diagnosis Index entries for D82.9

• Immunodeficiency › with › major defect

Nearby codes

• D82.1 Di George's syndrome
• D82.2 Immunodeficiency with short-limbed stature
• D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
• D82.4 Hyperimmunoglobulin E [IgE] syndrome
• D82.8 Immunodeficiency associated with other specified major defects
• D82.9 Immunodeficiency associated with major defect, unspecified (this code)