D89.82 Autoimmune lymphoproliferative syndrome [ALPS]

Billable ICD-10-CM code, FY2026.

Applies from D89 Other disorders involving the immune mechanism, not elsewhere classified

Excludes1 (never code together)

• hyperglobulinemia NOS (R77.1)
• monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 (not included here)

• transplant failure and rejection (T86.-)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 47 — Disorders of Immunity
• ESRD V24: HCC 47

MS-DRG index

Defines the logic of DRG(s) 545-547 in MDC 08.

Approximate ICD-9-CM (GEMs)

• 279.41 Autoimmune lymphoproliferative syndrome

Code annotations containing back-references to D89.82

Back-references to D89

• Type 1 Excludes: D72 Other disorders of white blood cells ("immunity disorders (D80-D89)")

Diagnosis Index entries for D89.82

• Autoimmune › lymphoproliferative syndrome [ALPS]
• Syndrome › autoimmune lymphoproliferative [ALPS]

Nearby codes

• D89.81 Graft-versus-host disease
• D89.810 Acute graft-versus-host disease
• D89.811 Chronic graft-versus-host disease
• D89.812 Acute on chronic graft-versus-host disease
• D89.813 Graft-versus-host disease, unspecified
• D89.82 Autoimmune lymphoproliferative syndrome [ALPS] (this code)
• D89.83 Cytokine release syndrome
• D89.831 Cytokine release syndrome, grade 1
• D89.832 Cytokine release syndrome, grade 2
• D89.833 Cytokine release syndrome, grade 3
• D89.834 Cytokine release syndrome, grade 4