D89.813 Graft-versus-host disease, unspecified

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from D89 Other disorders involving the immune mechanism, not elsewhere classified

Excludes1 (never code together)

• hyperglobulinemia NOS (R77.1)
• monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 (not included here)

• transplant failure and rejection (T86.-)

Applies from D89.81 Graft-versus-host disease

Code first

• underlying cause, such as:
• complications of transplanted organs and tissue (T86.-)
• complications of blood transfusion (T80.89)

Use additional code

• code to identify associated manifestations, such as:
• desquamative dermatitis (L30.8)
• diarrhea (R19.7)
• elevated bilirubin (R17)
• hair loss (L65.9)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 454 — Stem Cell, Including Bone Marrow, Transplant Status/Complications
• CMS-HCC V22: HCC 47 — Disorders of Immunity
• RxHCC V08: HCC 395 — Stem Cell, Including Bone Marrow, Transplant Status/Complications
• ESRD V24: HCC 47

MS-DRG index

Defines the logic of DRG(s) 808-810 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 279.50 Graft-versus-host disease, unspecified

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to D89.813

Back-references to D89.81

• Use Additional: M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA] ("graft versus host disease (D89.81-)")
• Use Additional: T80.89 Other complications following infusion, transfusion and therapeutic injection ("code to identify graft-versus-host reaction, if applicable, (D89.81-)")
• Use Additional: T86 Complications of transplanted organs and tissue ("graft-versus-host disease (D89.81-)")

Back-references to D89

• Type 1 Excludes: D72 Other disorders of white blood cells ("immunity disorders (D80-D89)")

Diagnosis Index entries for D89.813

• Disease, diseased › graft-versus-host (GVH)
• Disease, diseased › host-versus-graft
• Graft-versus-host disease

Nearby codes

• D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
• D89.81 Graft-versus-host disease
• D89.810 Acute graft-versus-host disease
• D89.811 Chronic graft-versus-host disease
• D89.812 Acute on chronic graft-versus-host disease
• D89.813 Graft-versus-host disease, unspecified (this code)
• D89.82 Autoimmune lymphoproliferative syndrome [ALPS]
• D89.83 Cytokine release syndrome
• D89.831 Cytokine release syndrome, grade 1
• D89.832 Cytokine release syndrome, grade 2
• D89.833 Cytokine release syndrome, grade 3