E01.1 Iodine-deficiency related multinodular (endemic) goiter

Billable ICD-10-CM code, FY2026.

Applicable to

• Iodine-deficiency related nodular goiter

Applies from E01 Iodine-deficiency related thyroid disorders and allied conditions

Excludes1 (never code together)

• congenital iodine-deficiency syndrome (E00.-)
• subclinical iodine-deficiency hypothyroidism (E02)

Risk adjustment (HCC)

• RxHCC V08: HCC 44 — Thyroid Disorders

MS-DRG index

Defines the logic of DRG(s) 643-645 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 241.1 Nontoxic multinodular goiter (approximate)

Code annotations containing back-references to E01.1

Back-references to E01.1

• Code First: D63.8 Anemia in other chronic diseases classified elsewhere ("hypothyroidism (E00.0-E03.9)")
• Code First: G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere ("cerebral degeneration (due to) hypothyroidism (E00.0-E03.9)")

Back-references to E01

• Type 1 Excludes: E03 Other hypothyroidism ("iodine-deficiency related hypothyroidism (E00-E02)")
• Type 1 Excludes: E04 Other nontoxic goiter ("iodine-deficiency related goiter (E00-E02)")
• Type 1 Excludes: E61 Deficiency of other nutrient elements ("iodine deficiency related thyroid disorders (E00-E02)")
• Code First: F02 Dementia in other diseases classified elsewhere ("hypothyroidism, acquired (E00-E03.-)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")
• Code Also: I27.29 Other secondary pulmonary hypertension ("hypothyroidism (E00-E03)")
• Code First: M14.8 Arthropathies in other specified diseases classified elsewhere ("hypothyroidism (E00-E03)")
• Type 2 Excludes: Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified ("iodine-deficiency-related hypothyroidism (E00-E02)")

Diagnosis Index entries for E01.1

• Goiter (plunging) (substernal) › cystic › due to iodine-deficiency
• Goiter (plunging) (substernal) › endemic (iodine-deficiency) › multinodular
• Goiter (plunging) (substernal) › iodine-deficiency (endemic) › multinodular
• Goiter (plunging) (substernal) › iodine-deficiency (endemic) › nodular
• Goiter (plunging) (substernal) › nodular (nontoxic) (due to) › endemic
• Goiter (plunging) (substernal) › nodular (nontoxic) (due to) › iodine-deficiency
• Struma › nodosa (simplex) › endemic › multinodular
• Struma › nodosa (simplex) › multinodular › iodine-deficiency related

Nearby codes

• E01 Iodine-deficiency related thyroid disorders and allied conditions
• E01.0 Iodine-deficiency related diffuse (endemic) goiter
• E01.1 Iodine-deficiency related multinodular (endemic) goiter (this code)
• E01.2 Iodine-deficiency related (endemic) goiter, unspecified
• E01.8 Other iodine-deficiency related thyroid disorders and allied conditions