E25.8 Other adrenogenital disorders

Billable ICD-10-CM code, FY2026.

Applicable to

• Idiopathic adrenogenital disorder

Use additional code

• code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Applies from E25 Adrenogenital disorders

Includes

• adrenogenital syndromes, virilizing or feminizing, whether acquired or due to adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
• Female adrenal pseudohermaphroditism
• Female heterosexual precocious pseudopuberty
• Male isosexual precocious pseudopuberty
• Male macrogenitosomia praecox
• Male sexual precocity with adrenal hyperplasia
• Male virilization (female)

Excludes1 (never code together)

• indeterminate sex and pseudohermaphroditism (Q56)
• chromosomal abnormalities (Q90-Q99)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 23 — Other Significant Endocrine and Metabolic Disorders
• RxHCC V08: HCC 43 — Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders
• ESRD V24: HCC 23

MS-DRG index

Defines the logic of DRG(s) 643-645 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 255.2 Adrenogenital disorders (approximate)

Code annotations containing back-references to E25.8

Back-references to E25

• Type 1 Excludes: E30.1 Precocious puberty ("female heterosexual precocious pseudopuberty (E25.-)")
• Type 1 Excludes: E30.1 Precocious puberty ("male isosexual precocious pseudopuberty (E25.-)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")
• Type 1 Excludes: Q56 Indeterminate sex and pseudohermaphroditism ("female pseudohermaphroditism with adrenocortical disorder (E25.-)")
• Type 1 Excludes: Q89.1 Congenital malformations of adrenal gland ("adrenogenital disorders (E25.-)")

Diagnosis Index entries for E25.8

• Adrenogenital syndrome › acquired
• Disorder (of) › adrenogenital › drug-induced
• Disorder (of) › adrenogenital › iatrogenic
• Disorder (of) › adrenogenital › idiopathic
• Pseudohermaphroditism › adrenal
• Pseudohermaphroditism › female › with adrenocortical disorder
• Pseudohermaphroditism › male › with › adrenocortical disorder
• Pseudohermaphroditism › male › adrenal
• Pseudopuberty, precocious › female heterosexual
• Pseudopuberty, precocious › male isosexual
• Puberty (development state) › premature › due to › adrenal cortical hyperfunction

Nearby codes

• E25 Adrenogenital disorders
• E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
• E25.8 Other adrenogenital disorders (this code)
• E25.9 Adrenogenital disorder, unspecified