E77.0 Defects in post-translational modification of lysosomal enzymes
Billable ICD-10-CM code, FY2026.
Applicable to
- Mucolipidosis II [I-cell disease]
- Mucolipidosis III [pseudo-Hurler polydystrophy]
Risk adjustment (HCC)
- CMS-HCC V22: HCC 23 — Other Significant Endocrine and Metabolic Disorders
- RxHCC V08: HCC 41 — Lysosomal Storage Disorders
- ESRD V24: HCC 23
MS-DRG index
Defines the logic of DRG(s) 642 in MDC 10.
Approximate ICD-9-CM (GEMs)
272.7 Lipidoses (approximate)
Code annotations containing back-references to E77.0
Back-references to E77.0
- Type 1 Excludes:
E75 Disorders of sphingolipid metabolism and other lipid storage disorders ("mucolipidosis, types I-III (E77.0-E77.1)")
Back-references to E77
- Type 2 Excludes:
G11 Hereditary ataxia ("metabolic disorders (E70-E88)") - Code First:
G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)") - Type 2 Excludes:
G71 Primary disorders of muscles ("metabolic disorders (E70-E88)") - Code First:
H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)") - Type 2 Excludes:
N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88") - Type 2 Excludes:
N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88") - Type 1 Excludes:
P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")
Diagnosis Index entries for E77.0
- Defect, defective › lysosomal enzyme, post-translational modification
- Defect, defective › modification, lysosomal enzymes, post-translational
- Disease, diseased › I-cell
- Disease, diseased › pseudo-Hurler's
- Mucolipidosis › II, III
- Polydystrophy, pseudo-Hurler
- Pseudo-Hurler's polydystrophy
Nearby codes
E77 Disorders of glycoprotein metabolismE77.0 Defects in post-translational modification of lysosomal enzymes (this code)E77.1 Defects in glycoprotein degradationE77.8 Other disorders of glycoprotein metabolismE77.9 Disorder of glycoprotein metabolism, unspecified