E80.5 Crigler-Najjar syndrome

Billable ICD-10-CM code, FY2026.

Applies from E80 Disorders of porphyrin and bilirubin metabolism

Includes

• defects of catalase and peroxidase

MS-DRG index

Defines the logic of DRG(s) 441-443 in MDC 07.

Approximate ICD-9-CM (GEMs)

• 277.4 Disorders of bilirubin excretion (approximate)

Code annotations containing back-references to E80.5

Back-references to E80.5

• Type 1 Excludes: P57.8 Other specified kernicterus ("Crigler-Najjar syndrome (E80.5)")

Back-references to E80

• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E80.5

• Crigler-Najjar disease or syndrome
• Deficiency, deficient › glucuronyl transferase
• Jaundice (yellow) › familial nonhemolytic (congenital) (Gilbert) › Crigler-Najjar
• Jaundice (yellow) › newborn › due to or associated with › Crigler-Najjar syndrome

Nearby codes

• E80.20 Unspecified porphyria
• E80.21 Acute intermittent (hepatic) porphyria
• E80.29 Other porphyria
• E80.3 Defects of catalase and peroxidase
• E80.4 Gilbert syndrome
• E80.5 Crigler-Najjar syndrome (this code)
• E80.6 Other disorders of bilirubin metabolism
• E80.7 Disorder of bilirubin metabolism, unspecified