G72.81 Critical illness myopathy

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Acute necrotizing myopathy
• Acute quadriplegic myopathy
• Intensive care (ICU) myopathy
• Myopathy of critical illness

Applies from G72 Other and unspecified myopathies

Excludes1 (never code together)

• arthrogryposis multiplex congenita (Q74.3)
• dermatopolymyositis (M33.-)
• ischemic infarction of muscle (M62.2-)
• myositis (M60.-)
• polymyositis (M33.2.-)

MS-DRG index

Defines the logic of DRG(s) 091-093 in MDC 01.

Approximate ICD-9-CM (GEMs)

• 359.81 Critical illness myopathy

Code annotations containing back-references to G72.81

Back-references to G72.81

• Use Additional: R65.11 Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction ("critical illness myopathy (G72.81)")
• Use Additional: R65.2 Severe sepsis ("critical illness myopathy (G72.81)")

Back-references to G72

• Code First: M62.84 Sarcopenia ("other and unspecified myopathies (G72.-)")

Diagnosis Index entries for G72.81

• Myopathy › acute › necrotizing
• Myopathy › acute › quadriplegic
• Myopathy › critical illness
• Myopathy › intensive care (ICU)
• Myopathy › of critical illness

Nearby codes

• G72.3 Periodic paralysis
• G72.4 Inflammatory and immune myopathies, not elsewhere classified
• G72.41 Inclusion body myositis [IBM]
• G72.49 Other inflammatory and immune myopathies, not elsewhere classified
• G72.8 Other specified myopathies
• G72.81 Critical illness myopathy (this code)
• G72.89 Other specified myopathies
• G72.9 Myopathy, unspecified