I67.3 Progressive vascular leukoencephalopathy

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Binswanger's disease

Applies from I67 Other cerebrovascular diseases

Excludes1 (never code together)

• Occlusion and stenosis of cerebral artery causing cerebral infarction (I63.3-I63.5-)
• Occlusion and stenosis of precerebral artery causing cerebral infarction (I63.2-)

Excludes2 (not included here)

• sequelae of the listed conditions (I69.8)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 127 — Dementia, Mild or Unspecified
• RxHCC V08: HCC 112 — Dementia, Except Alzheimer's Disease
• ESRD V24: HCC 52

MS-DRG index

Defines the logic of DRG(s) 056-057 in MDC 01.

Approximate ICD-9-CM (GEMs)

• 046.3 Progressive multifocal leukoencephalopathy (approximate)

Code annotations containing back-references to I67.3

Back-references to I67

• Type 1 Excludes: G31.84 Mild cognitive impairment of uncertain or unknown etiology ("cerebrovascular diseases (I60-I69)")
• Code First: G46 Vascular syndromes of brain in cerebrovascular diseases ("underlying cerebrovascular disease (I60-I69)")
• Type 2 Excludes: I10 Essential (primary) hypertension ("essential (primary) hypertension involving vessels of brain (I60-I69)")
• Type 2 Excludes: I15 Secondary hypertension ("secondary hypertension involving vessels of brain (I60-I69)")

Diagnosis Index entries for I67.3

• Binswanger's disease
• Leukoencephalopathy › Binswanger's
• Leukoencephalopathy › vascular, progressive

Nearby codes

• I67 Other cerebrovascular diseases
• I67.0 Dissection of cerebral arteries, nonruptured
• I67.1 Cerebral aneurysm, nonruptured
• I67.2 Cerebral atherosclerosis
• I67.3 Progressive vascular leukoencephalopathy (this code)
• I67.4 Hypertensive encephalopathy
• I67.5 Moyamoya disease
• I67.6 Nonpyogenic thrombosis of intracranial venous system
• I67.7 Cerebral arteritis, not elsewhere classified
• I67.8 Other specified cerebrovascular diseases