K76.82 Hepatic encephalopathy

Billable ICD-10-CM code, FY2026.

Applicable to

• Hepatic encephalopathy, NOS
• Hepatic encephalopathy without coma
• Hepatocerebral intoxication
• Portal-systemic encephalopathy

Excludes1 (never code together)

• acute and subacute hepatic failure with coma (K72.01)
• alcoholic hepatic failure with coma (K70.41)
• chronic hepatic failure with coma (K72.11)
• hepatic failure with coma (K72.91)

Code also

• underlying liver disease, such as:
• acute and subacute hepatic failure without coma (K72.00)
• alcoholic hepatic failure without coma (K70.40)
• chronic hepatic failure without coma (K72.10)
• hepatic failure with toxic liver disease without coma (K71.10)
• hepatic failure without coma (K72.90)
• icterus of newborn (P55-P59)
• postprocedural hepatic failure (K91.82)
• viral hepatitis without hepatic coma (B15.9, B16.1, B16.9, B17.10, B19.10, B19.20, B19.9)

Applies from K76 Other diseases of liver

Excludes2 (not included here)

• alcoholic liver disease (K70.-)
• amyloid degeneration of liver (E85.-)
• cystic disease of liver (congenital) (Q44.6)
• hepatic vein thrombosis (I82.0)
• hepatomegaly NOS (R16.0)
• pigmentary cirrhosis (of liver) (E83.110)
• portal vein thrombosis (I81)
• toxic liver disease (K71.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 63 — Chronic Liver Failure/End-Stage Liver Disorders
• CMS-HCC V22: HCC 27 — End-Stage Liver Disease
• ESRD V24: HCC 27

MS-DRG index

Defines the logic of DRG(s) 441-443 in MDC 07.

Diagnosis Index entries for K76.82

• Encephalopathy (acute) › hepatic (without coma)
• Encephalopathy (acute) › portal-systemic
• Intoxication › hepatocerebral

Nearby codes

• K76.5 Hepatic veno-occlusive disease
• K76.6 Portal hypertension
• K76.7 Hepatorenal syndrome
• K76.8 Other specified diseases of liver
• K76.81 Hepatopulmonary syndrome
• K76.82 Hepatic encephalopathy (this code)
• K76.89 Other specified diseases of liver
• K76.9 Liver disease, unspecified