M31.10 Thrombotic microangiopathy, unspecified

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Risk adjustment (HCC)

• CMS-HCC V28: HCC 112 — Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions
• CMS-HCC V22: HCC 40 — Rheumatoid Arthritis and Inflammatory Connective Tissue Disease
• RxHCC V08: HCC 84 — Systemic Lupus Erythematosus and Other Systemic Connective Tissue Disorders
• ESRD V24: HCC 40

MS-DRG index

Defines the logic of DRG(s) 545-547 in MDC 08.

Code annotations containing back-references to M31.10

Back-references to M31

• Type 2 Excludes: I77 Other disorders of arteries and arterioles ("collagen (vascular) diseases (M30-M36)")
• Type 2 Excludes: J82 Pulmonary eosinophilia, not elsewhere classified ("pulmonary eosinophilia due to systemic connective tissue disorders (M30-M36)")
• Code First: J84.170 Interstitial lung disease with progressive fibrotic phenotype in diseases classified elsewhere ("systemic connective tissue disorders (M30-M36)")
• Type 1 Excludes: L94 Other localized connective tissue disorders ("systemic connective tissue disorders (M30-M36)")

Diagnosis Index entries for M31.10

• Microangiopathy (peripheral) › thrombotic

Nearby codes

• M31 Other necrotizing vasculopathies
• M31.0 Hypersensitivity angiitis
• M31.1 Thrombotic microangiopathy
• M31.10 Thrombotic microangiopathy, unspecified (this code)
• M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]
• M31.19 Other thrombotic microangiopathy
• M31.2 Lethal midline granuloma
• M31.3 Wegener's granulomatosis
• M31.30 Wegener's granulomatosis without renal involvement