R53.82 Chronic fatigue, unspecified

Billable ICD-10-CM code, FY2026.

Excludes1 (never code together)

• chronic fatigue syndrome (G93.32)
• myalgic encephalomyelitis (G93.32)
• other post infection and related fatigue syndromes (G93.39)
• postviral fatigue syndrome (G93.31)

Applies from R53.8 Other malaise and fatigue

Excludes1 (never code together)

• combat exhaustion and fatigue (F43.0)
• congenital debility (P96.9)
• exhaustion and fatigue due to excessive exertion (T73.3)
• exhaustion and fatigue due to exposure (T73.2)
• exhaustion and fatigue due to heat (T67.-)
• exhaustion and fatigue due to pregnancy (O26.8-)
• exhaustion and fatigue due to recurrent depressive episode (F33-)
• exhaustion and fatigue due to senile debility (R54)

MS-DRG index

Defines the logic of DRG(s) 947-948 in MDC 23.

Approximate ICD-9-CM (GEMs)

• 780.71 Chronic fatigue syndrome

Code annotations containing back-references to R53.82

Back-references to R53.82

• Type 1 Excludes: G93.3 Postviral and related fatigue syndromes ("chronic fatigue NOS (R53.82)")

Diagnosis Index entries for R53.82

• Fatigue › chronic

Nearby codes

• R53.0 Neoplastic (malignant) related fatigue
• R53.1 Weakness
• R53.2 Functional quadriplegia
• R53.8 Other malaise and fatigue
• R53.81 Other malaise
• R53.82 Chronic fatigue, unspecified (this code)
• R53.83 Other fatigue