C92.10 Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Chronic myeloid leukemia, BCR/ABL-positive with failed remission
• Chronic myeloid leukemia, BCR/ABL-positive NOS

Applies from C92 Myeloid leukemia

Includes

• granulocytic leukemia
• myelogenous leukemia

Excludes1 (never code together)

• personal history of leukemia (Z85.6)

Code also

• , if applicable, pancytopenia (acquired) (D61.818)

Applies from C92.1 Chronic myeloid leukemia, BCR/ABL-positive

Applicable to

• Chronic myelogenous leukemia, Philadelphia chromosome (Ph1) positive
• Chronic myelogenous leukemia, t(9;22) (q34;q11)
• Chronic myelogenous leukemia with crisis of blast cells

Excludes1 (never code together)

• atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
• chronic myelomonocytic leukemia (C93.1-)
• chronic myeloproliferative disease (D47.1)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 22 — Bladder, Colorectal, and Other Cancers
• CMS-HCC V22: HCC 9 — Lung and Other Severe Cancers
• RxHCC V08: HCC 15 — Chronic Myeloid Leukemia
• ESRD V24: HCC 9

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 205.10 Chronic myeloid leukemia, without mention of having achieved remission (approximate)

Code annotations containing back-references to C92.10

Back-references to C92.10

• Type 1 Excludes: C92.0 Acute myeloblastic leukemia ("acute exacerbation of chronic myeloid leukemia (C92.10)")
• Code Also: I27.29 Other secondary pulmonary hypertension ("chronic myeloid leukemia (C92.10-C92.22)")

Back-references to C92.1

• Type 1 Excludes: D47.1 Chronic myeloproliferative disease ("chronic myeloid leukemia BCR/ABL-positive (C92.1-)")

Back-references to C92

• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: D72.8 Other specified disorders of white blood cells ("leukemia (C91-C95)")
• Type 1 Excludes: D72.825 Bandemia ("leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)")
• Code First: M36.1 Arthropathy in neoplastic disease ("leukemia (C91-C95)")
• Code First: N16 Renal tubulo-interstitial disorders in diseases classified elsewhere ("leukemia (C91-C95)")
• Code First: R50.81 Fever presenting with conditions classified elsewhere ("leukemia (C91-C95)")
• Type 1 Excludes: T66 Radiation sickness, unspecified ("leukemia (C91-C95)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C92.0 Acute myeloblastic leukemia
• C92.00 Acute myeloblastic leukemia, not having achieved remission
• C92.01 Acute myeloblastic leukemia, in remission
• C92.02 Acute myeloblastic leukemia, in relapse
• C92.1 Chronic myeloid leukemia, BCR/ABL-positive
• C92.10 Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission (this code)
• C92.11 Chronic myeloid leukemia, BCR/ABL-positive, in remission
• C92.12 Chronic myeloid leukemia, BCR/ABL-positive, in relapse
• C92.2 Atypical chronic myeloid leukemia, BCR/ABL-negative
• C92.20 Atypical chronic myeloid leukemia, BCR/ABL-negative, not having achieved remission
• C92.21 Atypical chronic myeloid leukemia, BCR/ABL-negative, in remission