D57.20 Sickle-cell/Hb-C disease without crisis

Billable ICD-10-CM code, FY2026.

Applies from D57 Sickle-cell disorders

Excludes1 (never code together)

• other hemoglobinopathies (D58.-)

Use additional code

• code for any associated fever (R50.81)

Applies from D57.2 Sickle-cell/Hb-C disease

Applicable to

• Hb-SC disease
• Hb-S/Hb-C disease

Risk adjustment (HCC)

• CMS-HCC V28: HCC 108 — Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major
• CMS-HCC V22: HCC 46 — Severe Hematological Disorders
• ESRD V24: HCC 46

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 282.63 Sickle-cell/Hb-C disease without crisis

Code annotations containing back-references to D57.20

Back-references to D57.2

• Code First: N08 Glomerular disorders in diseases classified elsewhere ("sickle-cell disease (D57.0-D57.8)")

Back-references to D57

• Type 1 Excludes: D56.8 Other thalassemias ("sickle-cell anemia (D57.-)")
• Code First: H36 Retinal disorders in diseases classified elsewhere ("sickle-cell disorders (D57.-)")
• Code First: M14.8 Arthropathies in other specified diseases classified elsewhere ("sickle-cell disorders (D57.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Code First: R50.81 Fever presenting with conditions classified elsewhere ("sickle-cell disease (D57.-)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")
• Code Also: Z71.87 Encounter for pediatric-to-adult transition counseling ("sickle-cell disorder (D57.-)")

Diagnosis Index entries for D57.20

• Disease, diseased › sickle-cell › Hb-C
• Disease, diseased › sickle-cell › Hb-C › without crisis

Nearby codes

• D57.03 Hb-SS disease with cerebral vascular involvement
• D57.04 Hb-SS disease with dactylitis
• D57.09 Hb-SS disease with crisis with other specified complication
• D57.1 Sickle-cell disease without crisis
• D57.2 Sickle-cell/Hb-C disease
• D57.20 Sickle-cell/Hb-C disease without crisis (this code)
• D57.21 Sickle-cell/Hb-C disease with crisis
• D57.211 Sickle-cell/Hb-C disease with acute chest syndrome
• D57.212 Sickle-cell/Hb-C disease with splenic sequestration
• D57.213 Sickle-cell/Hb-C disease with cerebral vascular involvement
• D57.214 Sickle-cell/Hb-C disease with dactylitis