D59.4 Other nonautoimmune hemolytic anemias

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Mechanical hemolytic anemia
• Microangiopathic hemolytic anemia
• Toxic hemolytic anemia

Risk adjustment (HCC)

• CMS-HCC V28: HCC 109 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
• CMS-HCC V22: HCC 46 — Severe Hematological Disorders
• RxHCC V08: HCC 96 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
• ESRD V24: HCC 46

MS-DRG index

Defines the logic of DRG(s) 791 in MDC 15.

Approximate ICD-9-CM (GEMs)

• 283.10 Non-autoimmune hemolytic anemia, unspecified (approximate)
• 283.19 Other non-autoimmune hemolytic anemias (approximate)

Code annotations containing back-references to D59.4

Back-references to D59

• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D59.4

• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › acquired › infectious
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › acquired › toxic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › due to › cardiac conditions
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › due to › presence of shunt or other internal prosthetic device
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › mechanical
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › microangiopathic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › nonautoimmune
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › secondary
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › symptomatic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › hemolytic › toxic
• Disease, diseased › nonautoimmune hemolytic
• Nonautoimmune hemolytic anemia
• Syndrome › erythrocyte fragmentation

Nearby codes

• D59.3 Hemolytic-uremic syndrome
• D59.30 Hemolytic-uremic syndrome, unspecified
• D59.31 Infection-associated hemolytic-uremic syndrome
• D59.32 Hereditary hemolytic-uremic syndrome
• D59.39 Other hemolytic-uremic syndrome
• D59.4 Other nonautoimmune hemolytic anemias (this code)
• D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
• D59.6 Hemoglobinuria due to hemolysis from other external causes
• D59.8 Other acquired hemolytic anemias
• D59.9 Acquired hemolytic anemia, unspecified