D64.1 Secondary sideroblastic anemia due to disease

Billable ICD-10-CM code, FY2026.

Code first

• underlying disease

Applies from D64 Other anemias

Excludes1 (never code together)

• refractory anemia (D46.-)
• refractory anemia with excess blasts in transformation [RAEB T] (C92.0-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 109 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• RxHCC V08: HCC 96 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 285.0 Sideroblastic anemia (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Manifestation codes as principal diagnosis: Manifestation codes describe the manifestation of an underlying disease, not the disease itself, and are not allowed as principal diagnosis.

Code annotations containing back-references to D64.1

Back-references to D64.1

• Type 1 Excludes: E83.1 Disorders of iron metabolism ("sideroblastic anemia (D64.0-D64.3)")

Back-references to D64

• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D64.1

• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › sideroblastic › secondary (due to) › disease

Nearby codes

• D64 Other anemias
• D64.0 Hereditary sideroblastic anemia
• D64.1 Secondary sideroblastic anemia due to disease (this code)
• D64.2 Secondary sideroblastic anemia due to drugs and toxins
• D64.3 Other sideroblastic anemias
• D64.4 Congenital dyserythropoietic anemia
• D64.8 Other specified anemias
• D64.81 Anemia due to antineoplastic chemotherapy