D68.4 Acquired coagulation factor deficiency

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Deficiency of coagulation factor due to liver disease
• Deficiency of coagulation factor due to vitamin K deficiency

Excludes1 (never code together)

• vitamin K deficiency of newborn (P53)

Applies from D68 Other coagulation defects

Excludes1 (never code together)

• abnormal coagulation profile NOS (R79.1)

Excludes2 (not included here)

• coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)
• coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 813 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 286.7 Acquired coagulation factor deficiency (approximate)

Code annotations containing back-references to D68.4

Back-references to D68.4

• Type 1 Excludes: E56.1 Deficiency of vitamin K ("deficiency of coagulation factor due to vitamin K deficiency (D68.4)")

Back-references to D68

• Type 1 Excludes: R79.1 Abnormal coagulation profile ("coagulation defects (D68.-)")

Diagnosis Index entries for D68.4

• Defect, defective › coagulation (factor) › acquired
• Defect, defective › coagulation (factor) › due to › liver disease
• Defect, defective › coagulation (factor) › due to › vitamin K deficiency
• Deficiency, deficient › AC globulin (congenital) (hereditary) › acquired
• Deficiency, deficient › coagulation NOS › acquired (any)
• Deficiency, deficient › coagulation NOS › due to › hyperprothrombinemia
• Deficiency, deficient › coagulation NOS › due to › liver disease
• Deficiency, deficient › coagulation NOS › due to › vitamin K deficiency
• Deficiency, deficient › factor › multiple (congenital) › acquired
• Deficiency, deficient › fibrin-stabilizing factor (congenital) (hereditary) › acquired
• Deficiency, deficient › labile factor (congenital) (hereditary) › acquired
• Deficiency, deficient › proaccelerin (congenital) (hereditary) › acquired
• Deficiency, deficient › proconvertin factor (congenital) (hereditary) › acquired
• Deficiency, deficient › prothrombin (congenital) (heredItary) › acquired
• Deficiency, deficient › stable factor (congenital) (hereditary) › acquired
• Fibrinopenia (hereditary) › acquired
• Hemophilia (classical) (familial) (hereditary) › calcipriva
• Hemophilia (classical) (familial) (hereditary) › nonfamilial
• Hyperprothrombinemia, causing coagulation factor deficiency
• Hypoprothrombinemia (congenital) (hereditary) (idiopathic) › acquired

Nearby codes

• D68.31 Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
• D68.311 Acquired hemophilia
• D68.312 Antiphospholipid antibody with hemorrhagic disorder
• D68.318 Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
• D68.32 Hemorrhagic disorder due to extrinsic circulating anticoagulants
• D68.4 Acquired coagulation factor deficiency (this code)
• D68.5 Primary thrombophilia
• D68.51 Activated protein C resistance
• D68.52 Prothrombin gene mutation
• D68.59 Other primary thrombophilia
• D68.6 Other thrombophilia