D68.69 Other thrombophilia

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• COVID-19 associated hypercoagulability
• Hypercoagulable states NEC
• Secondary hypercoagulable state NOS

Code also

• , if applicable, associated condition

Applies from D68 Other coagulation defects

Excludes1 (never code together)

• abnormal coagulation profile NOS (R79.1)

Excludes2 (not included here)

• coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1)
• coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)

Applies from D68.6 Other thrombophilia

Applicable to

• Other hypercoagulable states

Excludes1 (never code together)

• diffuse or disseminated intravascular coagulation [DIC] (D65)
• heparin induced thrombocytopenia (HIT) (D75.82-)
• hyperhomocysteinemia (E72.11)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 48 — Coagulation Defects and Other Specified Hematological Disorders
• ESRD V24: HCC 48

MS-DRG index

Defines the logic of DRG(s) 814-816 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 289.82 Secondary hypercoagulable state (approximate)

Code annotations containing back-references to D68.69

Back-references to D68.69

• Type 1 Excludes: D68.5 Primary thrombophilia ("secondary activated protein C resistance (D68.69)")
• Type 1 Excludes: D68.5 Primary thrombophilia ("secondary antiphospholipid antibody syndrome (D68.69)")
• Type 1 Excludes: D68.5 Primary thrombophilia ("secondary lupus anticoagulant with hypercoagulable state (D68.69)")
• Type 1 Excludes: D68.5 Primary thrombophilia ("secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)")
• Use Additional: U07.1 COVID-19 ("hypercoagulable states (D68.69)")
• Use Additional: U07.1 COVID-19 ("thrombophilia (D68.69)")

Back-references to D68

• Type 1 Excludes: R79.1 Abnormal coagulation profile ("coagulation defects (D68.-)")

Diagnosis Index entries for D68.69

• Hypercoagulable (state) › secondary
• Hypercoagulable (state) › specified NEC
• Thrombophilia › secondary NEC
• Thrombophilia › specified NEC

Nearby codes

• D68.52 Prothrombin gene mutation
• D68.59 Other primary thrombophilia
• D68.6 Other thrombophilia
• D68.61 Antiphospholipid syndrome
• D68.62 Lupus anticoagulant syndrome
• D68.69 Other thrombophilia (this code)
• D68.8 Other specified coagulation defects
• D68.9 Coagulation defect, unspecified