D89.0 Polyclonal hypergammaglobulinemia

Billable ICD-10-CM code, FY2026.

Applicable to

• Benign hypergammaglobulinemic purpura
• Polyclonal gammopathy NOS

Applies from D89 Other disorders involving the immune mechanism, not elsewhere classified

Excludes1 (never code together)

• hyperglobulinemia NOS (R77.1)
• monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes2 (not included here)

• transplant failure and rejection (T86.-)

Risk adjustment (HCC)

• RxHCC V08: HCC 99 — Immune Disorders

MS-DRG index

Defines the logic of DRG(s) 814-816 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 273.0 Polyclonal hypergammaglobulinemia

Code annotations containing back-references to D89.0

Back-references to D89.0

• Type 1 Excludes: D69 Purpura and other hemorrhagic conditions ("benign hypergammaglobulinemic purpura (D89.0)")
• Type 1 Excludes: D69 Purpura and other hemorrhagic conditions ("Waldenström hypergammaglobulinemic purpura (D89.0)")
• Type 1 Excludes: E88.0 Disorders of plasma-protein metabolism, not elsewhere classified ("polyclonal hypergammaglobulinemia (D89.0)")

Back-references to D89

• Type 1 Excludes: D72 Other disorders of white blood cells ("immunity disorders (D80-D89)")

Diagnosis Index entries for D89.0

• Gammopathy (of undetermined significance [MGUS]) › polyclonal
• Hypergammaglobulinemia › polyclonal
• Hypergammaglobulinemia › Waldenström
• Purpura › hypergammaglobulinemic (benign) (Waldenström)
• Waldenström › hypergammaglobulinemia

Nearby codes

• D89 Other disorders involving the immune mechanism, not elsewhere classified
• D89.0 Polyclonal hypergammaglobulinemia (this code)
• D89.1 Cryoglobulinemia
• D89.2 Hypergammaglobulinemia, unspecified
• D89.3 Immune reconstitution syndrome
• D89.4 Mast cell activation syndrome and related disorders
• D89.40 Mast cell activation, unspecified