E05.10 Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm

Billable ICD-10-CM code, FY2026.

Applies from E05 Thyrotoxicosis [hyperthyroidism]

Excludes1 (never code together)

• chronic thyroiditis with transient thyrotoxicosis (E06.2)
• neonatal thyrotoxicosis (P72.1)

Applies from E05.1 Thyrotoxicosis with toxic single thyroid nodule

Applicable to

• Thyrotoxicosis with toxic uninodular goiter

Risk adjustment (HCC)

• RxHCC V08: HCC 44 — Thyroid Disorders

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 242.10 Toxic uninodular goiter without mention of thyrotoxic crisis or storm

Code annotations containing back-references to E05.10

Back-references to E05.1

• Code First: I43 Cardiomyopathy in diseases classified elsewhere ("thyrotoxicosis (E05.0-E05.9-)")

Back-references to E05

• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")
• Code First: G73.3 Myasthenic syndromes in other diseases classified elsewhere ("thyrotoxicosis (E05.-)")
• Code First: G99.0 Autonomic neuropathy in diseases classified elsewhere ("hyperthyroidism (E05.-)")
• Code Also: I27.29 Other secondary pulmonary hypertension ("hyperthyroidism (E05.-)")
• Code First: M14.8 Arthropathies in other specified diseases classified elsewhere ("thyrotoxicosis [hyperthyroidism] (E05.-)")

Diagnosis Index entries for E05.10

• Goiter (plunging) (substernal) › uninodular (nontoxic) › toxic or with hyperthyroidism
• Hyperthyroidism (latent) (pre-adult) (recurrent) › with › goiter (diffuse) › nodular (multinodular) › uninodular
• Struma › nodosa (simplex) › toxic or with hyperthyroidism › uninodular
• Struma › nodosa (simplex) › toxicosa › uninodular
• Thyrotoxicosis (recurrent) › with › goiter (diffuse) › adenomatous uninodular
• Thyrotoxicosis (recurrent) › with › goiter (diffuse) › uninodular
• Thyrotoxicosis (recurrent) › with › single thyroid nodule

Nearby codes

• E05 Thyrotoxicosis [hyperthyroidism]
• E05.0 Thyrotoxicosis with diffuse goiter
• E05.00 Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm
• E05.01 Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm
• E05.1 Thyrotoxicosis with toxic single thyroid nodule
• E05.10 Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm (this code)
• E05.11 Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm
• E05.2 Thyrotoxicosis with toxic multinodular goiter
• E05.20 Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
• E05.21 Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
• E05.3 Thyrotoxicosis from ectopic thyroid tissue