E05.81 Other thyrotoxicosis with thyrotoxic crisis or storm

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applies from E05 Thyrotoxicosis [hyperthyroidism]

Excludes1 (never code together)

• chronic thyroiditis with transient thyrotoxicosis (E06.2)
• neonatal thyrotoxicosis (P72.1)

Applies from E05.8 Other thyrotoxicosis

Applicable to

• Overproduction of thyroid-stimulating hormone

Risk adjustment (HCC)

• RxHCC V08: HCC 44 — Thyroid Disorders

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 242.81 Thyrotoxicosis of other specified origin with mention of thyrotoxic crisis or storm (approximate)

Code annotations containing back-references to E05.81

Back-references to E05.8

• Type 1 Excludes: E22 Hyperfunction of pituitary gland ("overproduction of thyroid-stimulating hormone (E05.8-)")
• Code First: I43 Cardiomyopathy in diseases classified elsewhere ("thyrotoxicosis (E05.0-E05.9-)")

Back-references to E05

• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")
• Code First: G73.3 Myasthenic syndromes in other diseases classified elsewhere ("thyrotoxicosis (E05.-)")
• Code First: G99.0 Autonomic neuropathy in diseases classified elsewhere ("hyperthyroidism (E05.-)")
• Code Also: I27.29 Other secondary pulmonary hypertension ("hyperthyroidism (E05.-)")
• Code First: M14.8 Arthropathies in other specified diseases classified elsewhere ("thyrotoxicosis [hyperthyroidism] (E05.-)")

Diagnosis Index entries for E05.81

• Hypersecretion › hormone (s) › thyroid stimulating › with thyroid storm
• Hyperthyroidism (latent) (pre-adult) (recurrent) › specified NEC › with thyroid storm
• Thyrotoxicosis (recurrent) › due to › overproduction of thyroid-stimulating hormone › with thyroid storm
• Thyrotoxicosis (recurrent) › due to › specified cause NEC › with thyroid storm

Nearby codes

• E05.4 Thyrotoxicosis factitia
• E05.40 Thyrotoxicosis factitia without thyrotoxic crisis or storm
• E05.41 Thyrotoxicosis factitia with thyrotoxic crisis or storm
• E05.8 Other thyrotoxicosis
• E05.80 Other thyrotoxicosis without thyrotoxic crisis or storm
• E05.81 Other thyrotoxicosis with thyrotoxic crisis or storm (this code)
• E05.9 Thyrotoxicosis, unspecified
• E05.90 Thyrotoxicosis, unspecified without thyrotoxic crisis or storm
• E05.91 Thyrotoxicosis, unspecified with thyrotoxic crisis or storm