E87.1 Hypo-osmolality and hyponatremia

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Sodium [Na] deficiency

Excludes1 (never code together)

• syndrome of inappropriate secretion of antidiuretic hormone (E22.2)

Applies from E87 Other disorders of fluid, electrolyte and acid-base balance

Excludes1 (never code together)

• diabetes insipidus (E23.2)
• electrolyte imbalance associated with hyperemesis gravidarum (O21.1)
• electrolyte imbalance following ectopic or molar pregnancy (O08.5)
• familial periodic paralysis (G72.3)
• metabolic acidemia in newborn, unspecified (P19.9)

MS-DRG index

Defines the logic of DRG(s) 640-641 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 276.1 Hyposmolality and/or hyponatremia

Code annotations containing back-references to E87.1

Back-references to E87

• Use Additional: E86 Volume depletion ("code(s) for any associated disorders of electrolyte and acid-base balance (E87.-)")
• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")
• Type 2 Excludes: R79.1 Abnormal coagulation profile ("abnormality of fluid, electrolyte or acid-base balance (E86-E87)")

Diagnosis Index entries for E87.1

• Cramp (s) › salt-depletion
• Deficiency, deficient › natrium
• Deficiency, deficient › salt
• Deficiency, deficient › sodium (Na)
• Depletion › salt or sodium
• Findings, abnormal, inconclusive, without diagnosis › sodium (deficiency)
• Hyponatremia
• Hypo-osmolality
• Low › salt syndrome
• Syndrome › hyponatremic
• Syndrome › hyposmolality
• Syndrome › salt › depletion
• Syndrome › salt › low
• Syndrome › sick › cell

Nearby codes

• E87 Other disorders of fluid, electrolyte and acid-base balance
• E87.0 Hyperosmolality and hypernatremia
• E87.1 Hypo-osmolality and hyponatremia (this code)
• E87.2 Acidosis
• E87.20 Acidosis, unspecified
• E87.21 Acute metabolic acidosis
• E87.22 Chronic metabolic acidosis
• E87.29 Other acidosis