E87.22 Chronic metabolic acidosis

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Chronic lactic acidosis

Code first

• underlying etiology, if applicable

Applies from E87 Other disorders of fluid, electrolyte and acid-base balance

Excludes1 (never code together)

• diabetes insipidus (E23.2)
• electrolyte imbalance associated with hyperemesis gravidarum (O21.1)
• electrolyte imbalance following ectopic or molar pregnancy (O08.5)
• familial periodic paralysis (G72.3)
• metabolic acidemia in newborn, unspecified (P19.9)

Applies from E87.2 Acidosis

Excludes1 (never code together)

• diabetic acidosis - see categories E08-E10, E11, E13 with ketoacidosis

MS-DRG index

Defines the logic of DRG(s) 640-641 in MDC 10.

Code annotations containing back-references to E87.22

Back-references to E87.2

• Use Additional: G90.81 Serotonin syndrome ("metabolic acidosis (E87.2-)")

Back-references to E87

• Use Additional: E86 Volume depletion ("code(s) for any associated disorders of electrolyte and acid-base balance (E87.-)")
• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")
• Type 2 Excludes: R79.1 Abnormal coagulation profile ("abnormality of fluid, electrolyte or acid-base balance (E86-E87)")

Diagnosis Index entries for E87.22

• Acidosis (lactic) › lactic › chronic
• Acidosis (lactic) › metabolic NEC › chronic
• Disorder (of) › electrolyte (balance) NEC › acidosis (lactic) (metabolic) › chronic

Nearby codes

• E87.0 Hyperosmolality and hypernatremia
• E87.1 Hypo-osmolality and hyponatremia
• E87.2 Acidosis
• E87.20 Acidosis, unspecified
• E87.21 Acute metabolic acidosis
• E87.22 Chronic metabolic acidosis (this code)
• E87.29 Other acidosis
• E87.3 Alkalosis
• E87.4 Mixed disorder of acid-base balance
• E87.5 Hyperkalemia
• E87.6 Hypokalemia