C88.00 Waldenström macroglobulinemia not having achieved remission

Billable ICD-10-CM code, FY2026.

Applicable to

• Lymphoplasmacytic lymphoma with IgM-production, NOS
• Lymphoplasmacytic lymphoma with IgM-production not having achieved remission
• Lymphoplasmacytic lymphoma with IgM-production with failed remission
• Macroglobulinemia (idiopathic) (primary) NOS
• Macroglobulinemia (idiopathic) (primary) not having achieved remission
• Macroglobulinemia (idiopathic) (primary) with failed remission
• Waldenström macroglobulinemia NOS
• Waldenström macroglobulinemia with failed remission

Applies from C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas

Excludes1 (never code together)

• B-cell lymphoma, unspecified (C85.1-)
• personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Applies from C88.0 Waldenström macroglobulinemia

Applicable to

• Lymphoplasmacytic lymphoma with IgM-production
• Macroglobulinemia (idiopathic) (primary)

Excludes1 (never code together)

• small cell B-cell lymphoma (C83.0)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 21 — Lymphoma and Other Cancers
• CMS-HCC V22: HCC 23 — Other Significant Endocrine and Metabolic Disorders
• RxHCC V08: HCC 19 — Leukemias and Other Hematologic Cancers
• ESRD V24: HCC 23

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Code annotations containing back-references to C88.00

Back-references to C88.00

• Type 1 Excludes: C83.0 Small cell B-cell lymphoma ("Waldenström macroglobulinemia (C88.00)")
• Type 1 Excludes: E88.0 Disorders of plasma-protein metabolism, not elsewhere classified ("Waldenström macroglobulinemia (C88.00)")

Back-references to C88

• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: C77 Secondary and unspecified malignant neoplasm of lymph nodes ("malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas
• C88.0 Waldenstrom macroglobulinemia
• C88.00 Waldenstrom macroglobulinemia not having achieved remission (this code)
• C88.01 Waldenstrom macroglobulinemia, in remission
• C88.2 Heavy chain disease
• C88.20 Heavy chain disease not having achieved remission
• C88.21 Heavy chain disease, in remission
• C88.3 Immunoproliferative small intestinal disease