C88.20 Heavy chain disease not having achieved remission

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Franklin disease NOS
• Franklin disease not having achieved remission
• Franklin disease with failed remission
• Gamma heavy chain disease NOS
• Gamma heavy chain disease not having achieved remission
• Gamma heavy chain disease with failed remission
• Heavy chain disease NOS
• Heavy chain disease with failed remissionMu heavy chain disease not having achieved remission
• Mu heavy chain disease NOS
• Mu heavy chain disease not having achieved remission
• Mu heavy chain disease with failed remission

Applies from C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas

Excludes1 (never code together)

• B-cell lymphoma, unspecified (C85.1-)
• personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Applies from C88.2 Heavy chain disease

Applicable to

• Franklin disease
• Gamma heavy chain disease
• Mu heavy chain disease

Risk adjustment (HCC)

• CMS-HCC V28: HCC 21 — Lymphoma and Other Cancers
• CMS-HCC V22: HCC 10 — Lymphoma and Other Cancers
• RxHCC V08: HCC 21 — Lymphomas and Other Hematologic Cancers
• ESRD V24: HCC 10

MS-DRG index

Defines the logic of DRG(s) 820-822 in MDC 17.

Code annotations containing back-references to C88.20

Back-references to C88

• Type 1 Excludes: C76 Malignant neoplasm of other and ill-defined sites ("malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)")
• Type 1 Excludes: C77 Secondary and unspecified malignant neoplasm of lymph nodes ("malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)")
• Code First: Z15.0 Genetic susceptibility to malignant neoplasm (", if applicable, any current malignant neoplasm (C00-C75, C81-C96)")

Nearby codes

• C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas
• C88.0 Waldenstrom macroglobulinemia
• C88.00 Waldenstrom macroglobulinemia not having achieved remission
• C88.01 Waldenstrom macroglobulinemia, in remission
• C88.2 Heavy chain disease
• C88.20 Heavy chain disease not having achieved remission (this code)
• C88.21 Heavy chain disease, in remission
• C88.3 Immunoproliferative small intestinal disease
• C88.30 Immunoproliferative small intestinal disease not having achieved remission
• C88.31 Immunoproliferative small intestinal disease, in remission
• C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]