E10.649 Type 1 diabetes mellitus with hypoglycemia without coma

Billable ICD-10-CM code, FY2026.

Applies from E10 Type 1 diabetes mellitus

Includes

• brittle diabetes (mellitus)
• diabetes (mellitus) due to autoimmune process
• diabetes (mellitus) due to immune mediated pancreatic islet beta-cell destruction
• idiopathic diabetes (mellitus)
• juvenile onset diabetes (mellitus)
• ketosis-prone diabetes (mellitus)

Excludes1 (never code together)

• diabetes mellitus due to underlying condition (E08.-)
• drug or chemical induced diabetes mellitus (E09.-)
• gestational diabetes (O24.4-)
• hyperglycemia NOS (R73.9)
• neonatal diabetes mellitus (P70.2)
• postpancreatectomy diabetes mellitus (E13.-)
• postprocedural diabetes mellitus (E13.-)
• secondary diabetes mellitus NEC (E13.-)
• type 2 diabetes mellitus (E11.-)

Applies from E10.64 Type 1 diabetes mellitus with hypoglycemia

Use additional code

• code for hypoglycemia level, if applicable (E16.A-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 38 — Diabetes with Glycemic, Unspecified, or No Complications
• CMS-HCC V22: HCC 18 — Diabetes with Chronic Complications
• RxHCC V08: HCC 30 — Diabetes with Complications
• ESRD V24: HCC 18

MS-DRG index

Defines the logic of DRG(s) 008 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 250.81 Diabetes with other specified manifestations, type I [juvenile type], not stated as uncontrolled (approximate)

Code annotations containing back-references to E10.649

Back-references to E10.649

• Type 1 Excludes: E16.1 Other hypoglycemia ("diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649)")
• Type 1 Excludes: E16.2 Hypoglycemia, unspecified ("diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649)")

Back-references to E10

• Code First: D84.81 Immunodeficiency due to conditions classified elsewhere ("diabetes mellitus (E08-E13)")
• Type 1 Excludes: E08 Diabetes mellitus due to underlying condition ("type 1 diabetes mellitus (E10.-)")
• Type 1 Excludes: E09 Drug or chemical induced diabetes mellitus ("type 1 diabetes mellitus (E10.-)")
• Type 1 Excludes: E11 Type 2 diabetes mellitus ("type 1 diabetes mellitus (E10.-)")
• Type 1 Excludes: E13 Other specified diabetes mellitus ("diabetes (mellitus) due to autoimmune process (E10.-)")
• Type 1 Excludes: E13 Other specified diabetes mellitus ("diabetes (mellitus) due to immune mediated pancreatic islet beta-cell destruction (E10.-)")
• Type 1 Excludes: E13 Other specified diabetes mellitus ("type 1 diabetes mellitus (E10.-)")
• Type 1 Excludes: E74 Other disorders of carbohydrate metabolism ("diabetes mellitus (E08-E13)")
• Type 1 Excludes: E87.2 Acidosis ("diabetic acidosis - see categories E08-E10, E11, E13 with ketoacidosis")
• Type 1 Excludes: G54.5 Neuralgic amyotrophy ("neuralgic amyotrophy in diabetes mellitus (E08-E13 with .44)")
• Type 1 Excludes: G59 Mononeuropathy in diseases classified elsewhere ("diabetic mononeuropathy (E08-E13 with .41)")
• Type 1 Excludes: G63 Polyneuropathy in diseases classified elsewhere ("diabetes mellitus (E08-E13 with .42)")
• Type 1 Excludes: G99.0 Autonomic neuropathy in diseases classified elsewhere ("diabetic autonomic neuropathy (E08-E13 with .43)")
• Type 1 Excludes: H20.0 Acute and subacute iridocyclitis ("iridocyclitis, iritis, uveitis (due to) (in) diabetes mellitus (E08-E13 with .39)")
• Type 1 Excludes: I73.8 Other specified peripheral vascular diseases ("diabetic (peripheral) angiopathy (E08-E13 with .51-.52)")
• Type 1 Excludes: I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere ("diabetic (peripheral) angiopathy (E08-E13 with .51-.52)")
• Type 2 Excludes: I96 Gangrene, not elsewhere classified ("gangrene in diabetes mellitus (E08-E13 with .52)")
• Type 1 Excludes: L92.1 Necrobiosis lipoidica, not elsewhere classified ("necrobiosis lipoidica associated with diabetes mellitus (E08-E13 with .620)")
• Type 1 Excludes: L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere ("skin disorders in diabetes (E08-E13 with .62-)")
• Type 1 Excludes: M14 Arthropathies in other diseases classified elsewhere ("diabetes mellitus (E08-E13 with .61-)")
• Type 1 Excludes: M14.6 Charcôt's joint ("Charcôt's joint in diabetes mellitus (E08-E13 with .610)")
• Type 1 Excludes: M90 Osteopathies in diseases classified elsewhere ("diabetes mellitus (E08-E13 with .69-)")
• Type 1 Excludes: N08 Glomerular disorders in diseases classified elsewhere ("diabetes (E08-E13 with .21)")
• Type 1 Excludes: N16 Renal tubulo-interstitial disorders in diseases classified elsewhere ("renal tubular degeneration in diabetes (E08-E13 with .29)")
• Type 1 Excludes: N76.82 Fournier disease of vagina and vulva ("gangrene in diabetes mellitus (E08-E13 with .52)")
• Code Also: N76.82 Fournier disease of vagina and vulva (", if applicable, diabetes mellitus (E08-E13 with .9)")
• Use Additional: O24.0 Pre-existing type 1 diabetes mellitus, in pregnancy, childbirth and the puerperium ("code from category E10 to further identify any manifestations")
• Type 1 Excludes: Q45.3 Other congenital malformations of pancreas and pancreatic duct ("congenital diabetes mellitus (E10.-)")
• Type 1 Excludes: R40 Somnolence, stupor and coma ("somnolence, stupor and coma in diabetes (E08-E13)")
• Type 1 Excludes: R73 Elevated blood glucose level ("diabetes mellitus (E08-E13)")
• Type 1 Excludes: R73.0 Abnormal glucose ("diabetes mellitus (E08-E13)")

Diagnosis Index entries for E10.649

• Diabetes, diabetic (mellitus) (sugar) › type 1 › with › hypoglycemia

Nearby codes

• E10.63 Type 1 diabetes mellitus with oral complications
• E10.630 Type 1 diabetes mellitus with periodontal disease
• E10.638 Type 1 diabetes mellitus with other oral complications
• E10.64 Type 1 diabetes mellitus with hypoglycemia
• E10.641 Type 1 diabetes mellitus with hypoglycemia with coma
• E10.649 Type 1 diabetes mellitus with hypoglycemia without coma (this code)
• E10.65 Type 1 diabetes mellitus with hyperglycemia
• E10.69 Type 1 diabetes mellitus with other specified complication
• E10.8 Type 1 diabetes mellitus with unspecified complications
• E10.9 Type 1 diabetes mellitus without complications
• E10.A Type 1 diabetes mellitus, presymptomatic