E16.0 Drug-induced hypoglycemia without coma

Billable ICD-10-CM code, FY2026.

Excludes1 (never code together)

• diabetes with hypoglycemia without coma (E09.649)

Use additional code

• code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
• code for hypoglycemia level, if applicable (E16.A-)

MS-DRG index

Defines the logic of DRG(s) 643-645 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 251.1 Other specified hypoglycemia (approximate)

Code annotations containing back-references to E16.0

Back-references to E16

• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")

Diagnosis Index entries for E16.0

• Hypoglycemia (spontaneous) › drug-induced
• Hypoglycemia (spontaneous) › due to insulin
• Hypoglycemia (spontaneous) › iatrogenic
• Reaction › hypoglycemic, due to insulin

Nearby codes

• E16 Other disorders of pancreatic internal secretion
• E16.0 Drug-induced hypoglycemia without coma (this code)
• E16.1 Other hypoglycemia
• E16.2 Hypoglycemia, unspecified
• E16.3 Increased secretion of glucagon
• E16.4 Increased secretion of gastrin
• E16.8 Other specified disorders of pancreatic internal secretion