E16.9 Disorder of pancreatic internal secretion, unspecified

Billable ICD-10-CM code, FY2026.

Applicable to

• Islet-cell hyperplasia NOS
• Pancreatic endocrine cell hyperplasia NOS

Risk adjustment (HCC)

• RxHCC V08: HCC 66 — Pancreatic Disorders and Intestinal Malabsorption, Except Pancreatitis

MS-DRG index

Defines the logic of DRG(s) 643-645 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 251.9 Unspecified disorder of pancreatic internal secretion

Code annotations containing back-references to E16.9

Back-references to E16

• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")

Diagnosis Index entries for E16.9

• Disorder (of) › pancreatic internal secretion
• Hyperplasia, hyperplastic › pancreatic islet cells
• Increase, increased › secretion › pancreas, endocrine

Nearby codes

• E16.1 Other hypoglycemia
• E16.2 Hypoglycemia, unspecified
• E16.3 Increased secretion of glucagon
• E16.4 Increased secretion of gastrin
• E16.8 Other specified disorders of pancreatic internal secretion
• E16.9 Disorder of pancreatic internal secretion, unspecified (this code)
• E16.A Hypoglycemia level
• E16.A1 Hypoglycemia level 1
• E16.A2 Hypoglycemia level 2
• E16.A3 Hypoglycemia level 3