E88.02 Plasminogen deficiency

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Dysplasminogenemia
• Hypoplasminogenemia
• Type 1 plasminogen deficiency
• Type 2 plasminogen deficiency

Use additional code

• code for associated findings, such as:
• hydrocephalus (G91.4)
• otitis media (H67.-)
• respiratory disorder related to plasminogen deficiency (J99)

Code also

• , if applicable, ligneous conjunctivitis (H10.51-)

Applies from E88 Other and unspecified metabolic disorders

Excludes1 (never code together)

• histiocytosis X (chronic) (C96.6)

Use additional code

• codes for associated conditions

Applies from E88.0 Disorders of plasma-protein metabolism, not elsewhere classified

Excludes1 (never code together)

• monoclonal gammopathy (of undetermined significance) (D47.2)
• polyclonal hypergammaglobulinemia (D89.0)
• Waldenström macroglobulinemia (C88.00)

Excludes2 (not included here)

• disorder of lipoprotein metabolism (E78.-)

MS-DRG index

Defines the logic of DRG(s) 826-828 in MDC 17.

Code annotations containing back-references to E88.02

Back-references to E88.02

• Code First: G91.4 Hydrocephalus in diseases classified elsewhere ("plasminogen deficiency (E88.02)")
• Code Also: H10.51 Ligneous conjunctivitis ("plasminogen deficiency (E88.02)")
• Code First: H67 Otitis media in diseases classified elsewhere ("plasminogen deficiency (E88.02)")
• Code First: J99 Respiratory disorders in diseases classified elsewhere ("plasminogen deficiency (E88.02)")

Back-references to E88.0

• Type 1 Excludes: R77 Other abnormalities of plasma proteins ("disorders of plasma-protein metabolism (E88.0-)")

Back-references to E88

• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E88.02

• Deficiency, deficient › plasminogen (type 1) (type 2)
• Dysplasminogenemia
• Hypoplasminogenemia

Nearby codes

• E88 Other and unspecified metabolic disorders
• E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
• E88.01 Alpha-1-antitrypsin deficiency
• E88.02 Plasminogen deficiency (this code)
• E88.09 Other disorders of plasma-protein metabolism, not elsewhere classified
• E88.1 Lipodystrophy, not elsewhere classified
• E88.10 Lipodystrophy, unspecified
• E88.11 Partial lipodystrophy
• E88.12 Generalized lipodystrophy