E88.4 Mitochondrial metabolism disorders

Non-billable header with 5 child codes.

Excludes1 (never code together)

• disorders of pyruvate metabolism (E74.4)
• Kearns-Sayre syndrome (H49.81)
• Leber's disease (H47.22)
• Leigh's encephalopathy (G31.82)
• Mitochondrial myopathy, NEC (G71.3)
• Reye's syndrome (G93.7)

Applies from E88 Other and unspecified metabolic disorders

Excludes1 (never code together)

• histiocytosis X (chronic) (C96.6)

Use additional code

• codes for associated conditions

Codes under E88.4

• E88.40 Mitochondrial metabolism disorder, unspecified
• E88.41 MELAS syndrome
• E88.42 MERRF syndrome
• E88.43 Disorders of mitochondrial tRNA synthetases
• E88.49 Other mitochondrial metabolism disorders

Code annotations containing back-references to E88.4

Back-references to E88.4

• Type 1 Excludes: G71.3 Mitochondrial myopathy, not elsewhere classified ("mitochondrial metabolism disorders (E88.4.-)")

Back-references to E88

• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Nearby codes

• E88.13 Localized lipodystrophy
• E88.14 HIV-associated lipodystrophy
• E88.19 Other lipodystrophy, not elsewhere classified
• E88.2 Lipomatosis, not elsewhere classified
• E88.3 Tumor lysis syndrome
• E88.4 Mitochondrial metabolism disorders (this code)
• E88.40 Mitochondrial metabolism disorder, unspecified
• E88.41 MELAS syndrome
• E88.42 MERRF syndrome
• E88.43 Disorders of mitochondrial tRNA synthetases
• E88.49 Other mitochondrial metabolism disorders