E88.2 Lipomatosis, not elsewhere classified

Billable ICD-10-CM code, FY2026.

Applicable to

• Lipomatosis NOS
• Lipomatosis (Check) dolorosa [Dercum]

Applies from E88 Other and unspecified metabolic disorders

Excludes1 (never code together)

• histiocytosis X (chronic) (C96.6)

Use additional code

• codes for associated conditions

Risk adjustment (HCC)

• RxHCC V08: HCC 47 — Disorders of Lipoid Metabolism

MS-DRG index

Defines the logic of DRG(s) 642 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 272.8 Other disorders of lipoid metabolism (approximate)

Code annotations containing back-references to E88.2

Back-references to E88.2

• Type 2 Excludes: E66 Overweight and obesity ("lipomatosis dolorosa [Dercum] (E88.2)")
• Type 2 Excludes: E66 Overweight and obesity ("lipomatosis NOS (E88.2)")

Back-references to E88

• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E88.2

• Adiposis › dolorosa
• Dercum's disease
• Lipomatosis
• Lipomatosis › dolorosa (Dercum)

Nearby codes

• E88.11 Partial lipodystrophy
• E88.12 Generalized lipodystrophy
• E88.13 Localized lipodystrophy
• E88.14 HIV-associated lipodystrophy
• E88.19 Other lipodystrophy, not elsewhere classified
• E88.2 Lipomatosis, not elsewhere classified (this code)
• E88.3 Tumor lysis syndrome
• E88.4 Mitochondrial metabolism disorders
• E88.40 Mitochondrial metabolism disorder, unspecified
• E88.41 MELAS syndrome
• E88.42 MERRF syndrome