F78.A1 SYNGAP1-related intellectual disability

Billable ICD-10-CM code, FY2026.

Code also

• , if applicable, any associated:
• autism spectrum disorder (F84.0)
• autistic disorder (F84.0)
• encephalopathy (G93.4-)
• epilepsy and recurrent seizures (G40.-)
• other pervasive developmental disorders (F84.8)
• pervasive developmental disorder, NOS (F84.9)

Risk adjustment (HCC)

• RxHCC V08: HCC 147 — Moderate Intellectual Disability/Developmental Disorder

MS-DRG index

Defines the logic of DRG(s) 884 in MDC 19.

Code annotations containing back-references to F78.A1

Back-references to F78

• Use Additional: E00 Congenital iodine-deficiency syndrome ("code (F70-F79) to identify associated intellectual disabilities.")
• Type 2 Excludes: F80.0 Phonological disorder ("speech articulation impairment due to intellectual disabilities (F70-F79)")
• Type 2 Excludes: F80.1 Expressive language disorder ("intellectual disabilities (F70-F79)")
• Type 2 Excludes: F80.2 Mixed receptive-expressive language disorder ("intellectual disabilities (F70-F79)")
• Type 2 Excludes: F82 Specific developmental disorder of motor function ("lack of coordination secondary to intellectual disabilities (F70-F79)")
• Code Also: G93.45 Developmental and epileptic encephalopathy ("intellectual disabilities (F70-F79)")
• Code Also: Q87.85 MED13L syndrome ("intellectual disability (F70-F79)")
• Use Additional: Q87.87 Hao-Fountain Syndrome ("intellectual disabilities (F70-F79)")
• Use Additional: Q87.88 CTNNB1 syndrome ("intellectual disability (F70-F79)")
• Use Additional: Q90 Down syndrome ("code(s) to identify any associated degree of intellectual disabilities (F70-F79)")
• Use Additional: Q93.52 Phelan-McDermid syndrome ("degree of intellectual disabilities (F70-F79)")
• Code Also: QA0 Neurodevelopmental disorders related to specific genetic pathogenic variants ("intellectual disabilities (F70-F79)")
• Type 1 Excludes: R41.83 Borderline intellectual functioning ("intellectual disabilities (F70-F79)")
• Code Also: Z15.1 Genetic susceptibility to epilepsy and neurodevelopmental disorders ("intellectual disabilities (F70-F79)")
• Code First: Z91.83 Wandering in diseases classified elsewhere ("intellectual disabilities (F70-F79)")

Diagnosis Index entries for F78.A1

• Disability, disabilities › intellectual › with › pathogenic SYNGAP1 (genetic) (variant)
• Disability, disabilities › intellectual › genetic related › with › pathogenic SYNGAP1 (variant)
• Disability, disabilities › intellectual › genetic related › SYNGAP1-related
• Disability, disabilities › intellectual › SYNGAP1-related

Nearby codes

• F78 Other intellectual disabilities
• F78.A Other genetic related intellectual disabilities
• F78.A1 SYNGAP1-related intellectual disability (this code)
• F78.A9 Other genetic related intellectual disability