G93.45 Developmental and epileptic encephalopathy

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Early infantile epileptic encephalopathy

Code also

• , if applicable, associated disorders such as:
• developmental disorders of scholastic skills (F81.-)
• developmental disorder of speech and language (F80.-)
• epilepsy, by specific type (G40.-)
• intellectual disabilities (F70-F79)
• other neurodevelopmental disorder (F88)
• pervasive developmental disorders (F84.-)

Applies from G93.4 Other and unspecified encephalopathy

Excludes2 (not included here)

• alcoholic encephalopathy (G31.2)
• encephalopathy in diseases classified elsewhere (G94)
• hypertensive encephalopathy (I67.4)
• toxic (metabolic) encephalopathy (G92.8)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 201 — Seizure Disorders and Convulsions
• CMS-HCC V22: HCC 79 — Seizure Disorders and Convulsions
• RxHCC V08: HCC 164 — Epilepsy and Other Seizure Disorders, Except Intractable Epilepsy
• ESRD V24: HCC 79

MS-DRG index

Defines the logic of DRG(s) 070-072 in MDC 01.

Code annotations containing back-references to G93.45

Back-references to G93.45

• Code Also: QA0 Neurodevelopmental disorders related to specific genetic pathogenic variants ("developmental and epileptic encephalopathy (G93.45)")
• Code Also: Z15.1 Genetic susceptibility to epilepsy and neurodevelopmental disorders ("developmental and epileptic encephalopathy (G93.45)")

Back-references to G93.4

• Code Also: F78.A1 SYNGAP1-related intellectual disability ("encephalopathy (G93.4-)")

Diagnosis Index entries for G93.45

• Encephalopathy (acute) › developmental and epileptic
• Encephalopathy (acute) › early infantile epileptic

Nearby codes

• G93.40 Encephalopathy, unspecified
• G93.41 Metabolic encephalopathy
• G93.42 Megalencephalic leukoencephalopathy with subcortical cysts
• G93.43 Leukoencephalopathy with calcifications and cysts
• G93.44 Adult-onset leukodystrophy with axonal spheroids
• G93.45 Developmental and epileptic encephalopathy (this code)
• G93.49 Other encephalopathy
• G93.5 Compression of brain
• G93.6 Cerebral edema
• G93.7 Reye's syndrome
• G93.8 Other specified disorders of brain